CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10465
Family Name Arachidonate 5-lipoxygenase-activating protein inhibitor 2-[[4-(2-methyltetrazol-5-yl)-3-[(1S,3R,4S)-3-phenyl-3-bicyclo[2.2.1]heptanyl]phenoxy]methyl]quinoline family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00402351 Functional Category Bioactive
Superfamily Arachidonate 5-lipoxygenase-activating protein Binder Superfamily
Class Class 3578

Cousin Family NamesSeedsMembers
Cysteinyl leukotriene receptor 1 ligand SureCN7808360 family 4 11
Leukotriene B4 receptor 1 ligand AGN-PC-075N6M family 2 4
Cysteinyl leukotriene receptor 1 ligand SureCN7008285 family 12 97
Cysteinyl leukotriene receptor 1 ligand 2-[[3-[[3-methoxy-5-(2... 8 0
Cysteinyl leukotriene receptor 1 ligand 7-[[3-(quinolin-2-ylme... 7 5
Cysteinyl leukotriene receptor 1 ligand AGN-PC-03MOKX family 2 2
Type-1 angiotensin II receptor ligand methyl 2-methyl-6-propyl... 7 10
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 7 1
Type-1 angiotensin II receptor ligand 2-ethyl-6-methoxy-N-[[4-... 2 0
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 4 0
Type-1 angiotensin II receptor ligand 2-[(2-methyl-5,6,7,8-tet... 5 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 3


External ID

Functional Category

Molecule Name

CFAMM00402351 CHEMBL2031653 Bioactive 2-[[4-(2-methyltetrazol-5-yl)-3-[(1S,3R,4S)-3-phenyl-3-bicyclo[2.2.1]heptanyl]phenoxy]methyl]quinoline
CFAMM00402355 CHEMBL2031656 Bioactive 2-[[4-[2-(difluoromethyl)tetrazol-5-yl]-3-[(1S,3R,4S)-3-phenyl-3-bicyclo[2.2.1]heptanyl]phenoxy]methyl]quinoline
CFAMM00402354 CHEMBL2031654 Bioactive 2-[[4-(2-ethyltetrazol-5-yl)-3-[(1S,3R,4S)-3-phenyl-3-bicyclo[2.2.1]heptanyl]phenoxy]methyl]quinoline
CFAMM00402353 CHEMBL2031655 Bioactive 2-[[3-[(1S,3R,4S)-3-phenyl-3-bicyclo[2.2.1]heptanyl]-4-(2-propan-2-yltetrazol-5-yl)phenoxy]methyl]quinoline
CFAMM00402352 CHEMBL2031652 Bioactive 2-[[3-[(1S,3R,4S)-3-phenyl-3-bicyclo[2.2.1]heptanyl]-4-(2H-tetrazol-5-yl)phenoxy]methyl]quinoline

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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