CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10476
Family Name Hepatocyte growth factor receptor and Vascular endothelial growth factor receptor 2 ligand N-[5-(7-methoxyquinolin-4-yl)oxypyridin-2-yl]-1,5-dimethyl-3-oxo-2-phenylpyrazole-4-carboxamide family
No. of Seeds 15 No. of Other Members 0
Family Centroid CFAMM00401705 Functional Category Bioactive
Superfamily Hepatocyte growth factor receptor and Vascular endothelial growth factor receptor 2 Binder Superfamily
Class Class 938

Cousin Family NamesSeedsMembers
Alpha-1D adrenergic receptor Ligand Terazosin Family 28 638
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Hepatocyte growth factor receptor and Vascular endothelial gro... 28 178
Receptor tyrosine-protein kinase erbB-2 Inhibitor CP-724714 Fa... 4 180
Vascular endothelial growth factor receptor 2 Ligand Cediranib... 8 38
Tivozanib family 4 6
Platelet-derived growth factor receptor alpha and Platelet-der... 2 17
3-phosphoinositide-dependent protein kinase 1 and Ribosomal pr... 10 4
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN12658... 3 19
Equilibrative nucleoside transporter 1 inhibitor SureCN9046933... 2 9
Ephrin type-B receptor 4 ligand SureCN5131922 family 4 0
Integrin alpha-V and Integrin beta-5 inhibitor SureCN2491273 f... 11 10
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075FPC ... 6 1
Vascular endothelial growth factor receptor 3 and Platelet-der... 8 13
Platelet-derived growth factor receptor beta and Receptor-type... 6 5
Platelet-derived growth factor receptor beta and Receptor-type... 5 1
Platelet-derived growth factor receptor beta and Macrophage co... 7 0
Platelet-derived growth factor receptor alpha and Mast/stem ce... 2 2
Hepatocyte growth factor receptor and Vascular endothelial gro... 14 10
Protein-tyrosine kinase 2-beta and Focal adhesion kinase 1 inh... 3 6
Vascular endothelial growth factor receptor 2 and Aurora kinas... 4 3
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4463897 f... 3 2
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 9 2
Receptor tyrosine-protein kinase erbB-2 ligand SureCN3374869 f... 4 8
Vascular endothelial growth factor receptor 2 ligand 6-(6,7-di... 4 0
Vascular endothelial growth factor receptor 2 and Cytochrome P... 2 1
Vascular endothelial growth factor receptor 2 and Tyrosine-pro... 4 0
Epidermal growth factor receptor ligand SureCN2989664 family 5 2
Vascular endothelial growth factor receptor 2 ligand AGN-PC-00... 9 2
Vascular endothelial growth factor receptor 2 ligand AGN-PC-00... 4 0
TGF-beta receptor type-1 ligand SureCN373216 family 3 14


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

38795 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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