CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10498
Family Name Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Protein farnesyltransferase subunit beta inhibitor AGN-PC-03PBRK family
No. of Seeds 13 No. of Other Members 1
Family Centroid CFAMM00402519 Functional Category Bioactive
Superfamily Protein farnesyltransferase subunit beta and Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha Binder Superfamily 12
Class Class 3779

Cousin Family NamesSeedsMembers
Farnesyltransferase beta subunit, putative Inhibitor Zarnestra... 10 56
Vascular endothelial growth factor receptor 2 Ligand XL999 Family 11 87
Farnesyltransferase beta subunit, putative and Protein farnesy... 20 81
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Thromboxane-A synthase Inhibitor 2-(6-imidazol-1-yl-hexyl)-iso... 3 6
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Lysosomal Pro-X carboxypeptidase inhibitor N-[(2S)-1-[(2S)-2-(... 1 0
Prelamin-A/C inhibitor CHEMBL1611943 family 1 9
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 6 3
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 9 3
Prothrombin and Cationic trypsin inhibitor (2S)-1-[(2R)-3,3-di... 5 9
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 7 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
5-hydroxytryptamine receptor 2B ligand SureCN1299437 family 6 7
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 3
Glucocorticoid receptor ligand SureCN13513652 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00402518 CHEMBL207784 Bioactive AGN-PC-03PBRN
CFAMM00402511 CHEMBL378462 Bioactive SureCN7661571
CFAMM00402517 CHEMBL203374 Bioactive AGN-PC-03PBS3
CFAMM00402510 CHEMBL381607 Bioactive AGN-PC-03PBRY
CFAMM00402516 CHEMBL381835 Bioactive AGN-PC-03PBSV
CFAMM00402509 CHEMBL204674 Bioactive AGN-PC-03PBSO
CFAMM00402522 CHEMBL380313 Bioactive AGN-PC-03PBST
CFAMM00402515 CHEMBL208266 Bioactive AGN-PC-03PBRH
CFAMM00402521 CHEMBL205973 Bioactive AGN-PC-03PBQQ
CFAMM00402514 CHEMBL206795 Bioactive AGN-PC-03PBRZ
CFAMM00402520 CHEMBL438264 Bioactive AGN-PC-03PBSF
CFAMM00402519 CHEMBL381133 Bioactive AGN-PC-03PBRK
CFAMM00402512 CHEMBL381490 Bioactive AGN-PC-03PBSJ

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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