CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10537
Family Name Glutamate receptor ionotropic, NMDA 2B ligand SureCN5351665 family
No. of Seeds 5 No. of Other Members 4
Family Centroid CFAMM00402666 Functional Category Bioactive
Superfamily Glutamate receptor ionotropic, NMDA 2B and Cytochrome P450 2D6 Binder Superfamily
Class Class 3307

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor N-benzyl-2-morpholinopyrimidin-... 6 16
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2J2 inhib... 1 7
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-3-[5-methy... 4 5
Metabotropic glutamate receptor 5 ligand AGN-PC-075X3Y family 2 6
Rho-associated protein kinase 1 inhibitor AGN-PC-07COKD family 1 0
Sigma non-opioid intracellular receptor 1 and Alpha-1B adrener... 2 1
Glutamate receptor ionotropic, NMDA 2B and Cytochrome P450 2D6... 1 0


External ID

Functional Category

Molecule Name

CFAMM00402666 CHEMBL218713 Bioactive SureCN5351665
CFAMM00402671 CHEMBL2036513 Bioactive (4-methylphenyl)methyl (3S,4R)-3-fluoranyl-4-[(pyrimidin-2-ylamino)methyl]piperidine-1-carboxylate
CFAMM00402670 CHEMBL2036514 Bioactive (4-methylphenyl)methyl (3S,4S)-3-fluoranyl-4-[(pyrimidin-2-ylamino)methyl]piperidine-1-carboxylate
CFAMM00402669 CHEMBL218211 Bioactive (4-ethylphenyl)methyl 4-[(pyrimidin-2-ylamino)methyl]piperidine-1-carboxylate
CFAMM00402668 CHEMBL386184 Bioactive (4-propan-2-ylphenyl)methyl 4-[(pyrimidin-2-ylamino)methyl]piperidine-1-carboxylate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



80867 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543