CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10553
Family Name Serine/threonine-protein kinase Chk1 inhibitor 2-(1H-indol-5-yl)-N-(2-piperazin-1-ylphenyl)-1,3-thiazole-4-carboxamide family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00402791 Functional Category Bioactive
Superfamily Adenosine receptor A1 and Adenosine receptor A2a Ligand Kuanoniamine D Superfamily
Class Class 2909

Cousin Family NamesSeedsMembers
Macrophage metalloelastase Inhibitor PF-00356231 Family 5 79
Cathepsin B and Cathepsin K Inhibitor L-006235-1 Family 19 75
Coagulation factor X and Prothrombin inhibitor SureCN763988 fa... 31 86
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 13
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 1
Neuronal acetylcholine receptor subunit alpha-7 ligand AGN-PC-... 7 1
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 9 16
Orexin receptor type 2 and Orexin receptor type 1 ligand (2-me... 3 1
Orexin receptor type 1 and Orexin receptor type 2 ligand N-[[(... 9 5
Serine/threonine-protein kinase Chk1 inhibitor 2-(1-benzothiop... 4 6
Cathepsin K and Cathepsin L1 inhibitor (2R)-N-(cyanomethyl)-4-... 2 1
D(3) dopamine receptor and D(2) dopamine receptor ligand [4-[2... 6 5
Histone deacetylase 1 inhibitor 5-[5-[[(2-chlorophenyl)methyla... 4 1
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 4 4
Serine/threonine-protein kinase Chk1 inhibitor 2-(1,3-dihydroi... 2 5
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 4 0
Platelet-activating factor receptor ligand N,N-diethyl-3-[(4R)... 11 0
Epidermal growth factor receptor and Vascular endothelial grow... 14 19
Coagulation factor X inhibitor SureCN1253902 family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00402790 CHEMBL2381110 Bioactive 2-(1H-indol-5-yl)-N-(4-piperazin-1-ylpyridin-3-yl)-1,3-thiazole-4-carboxamide
CFAMM00402791 CHEMBL2037112 Bioactive 2-(1H-indol-5-yl)-N-(2-piperazin-1-ylphenyl)-1,3-thiazole-4-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

44341 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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