CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10554
Family Name Serine/threonine-protein kinase Chk1 inhibitor 2-(1-benzothiophen-5-yl)-N-(4-piperazin-1-ylpyridin-3-yl)-1,3-thiazole-4-carboxamide family
No. of Seeds 4 No. of Other Members 6
Family Centroid CFAMM00402795 Functional Category Bioactive
Superfamily Adenosine receptor A1 and Adenosine receptor A2a Ligand Kuanoniamine D Superfamily
Class Class 2909

Cousin Family NamesSeedsMembers
Cathepsin B and Cathepsin K Inhibitor L-006235-1 Family 19 75
Coagulation factor X inhibitor SureCN1652565 family 3 19
Coagulation factor X inhibitor AGN-PC-00FNCN family 3 3
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 13
Serine/threonine-protein kinase Chk1 inhibitor 2-(1H-indol-5-y... 2 2
Cathepsin K and Cathepsin L1 inhibitor (2R)-N-(cyanomethyl)-4-... 2 1
Serine/threonine-protein kinase Chk1 inhibitor 2-(1,3-dihydroi... 2 5
Coagulation factor X inhibitor SureCN1652235 family 1 0
Coagulation factor X inhibitor N-[2-oxo-1-(1H-pyrrolo[2,3-c]py... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00402804 CHEMBL2381112 Bioactive 2-(1-benzothiophen-2-yl)-N-(4-piperazin-1-ylpyridin-3-yl)-1,3-thiazole-4-carboxamide
CFAMM00402802 CHEMBL2037114 Bioactive 2-(1-benzothiophen-2-yl)-N-(2-piperazin-1-ylphenyl)-1,3-thiazole-4-carboxamide
CFAMM00402795 CHEMBL2381111 Bioactive 2-(1-benzothiophen-5-yl)-N-(4-piperazin-1-ylpyridin-3-yl)-1,3-thiazole-4-carboxamide
CFAMM00402801 CHEMBL2037113 Bioactive 2-(1-benzothiophen-5-yl)-N-(2-piperazin-1-ylphenyl)-1,3-thiazole-4-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27511 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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