CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10555
Family Name Sphingosine 1-phosphate receptor 1 ligand 7-(2-hydroxyethyl)-1-methyl-4-oxo-N-[4-phenyl-3-(trifluoromethyl)phenyl]quinoline-3-carboxamide family
No. of Seeds 2 No. of Other Members 10
Family Centroid CFAMM00402814 Functional Category Bioactive
Superfamily Sphingosine 1-phosphate receptor 1 and Protease Binder Superfamily
Class Class 1365

Cousin Family NamesSeedsMembers
Histone deacetylase 1 Inhibitor AN-9 Family 31 282
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 15 129
3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-ster... 4 8
C-C chemokine receptor type 2 ligand N-[2-[[(2S,3S)-1-[(2,4-di... 13 8
Microsomal triglyceride transfer protein large subunit inhibit... 8 1
Protease and Replicase polyprotein 1a inhibitor AC1LALLS family 1 0
Glycogen phosphorylase, liver form inhibitor SureCN5195475 family 9 5
Glycogen phosphorylase, liver form inhibitor AGN-PC-00CDLB family 2 0
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 1 1
Muscarinic acetylcholine receptor M1 ligand 5-fluoro-4-oxo-1-[... 1 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00402814 CHEMBL2037124 Bioactive 7-(2-hydroxyethyl)-1-methyl-4-oxo-N-[4-phenyl-3-(trifluoromethyl)phenyl]quinoline-3-carboxamide
CFAMM00402807 CHEMBL2037128 Bioactive 3-[1-methyl-4-oxo-3-[[4-phenyl-3-(trifluoromethyl)phenyl]carbamoyl]quinolin-7-yl]propanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27075 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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