CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10556
Family Name Serine/threonine-protein kinase pim-1 and Serine/threonine-protein kinase pim-3 inhibitor (3E)-5-chloro-3-[[5-[3-(4-methyl-1,4-diazepane-1-carbonyl)phenyl]furan-2-yl]methylidene]-1H-indol-2-one family
No. of Seeds 3 No. of Other Members 6
Family Centroid CFAMM00402824 Functional Category Bioactive
Superfamily Prelamin-A/C and Cellular tumor antigen p53 Binder Superfamily 9
Class Class 3361

Cousin Family NamesSeedsMembers
Sodium channel protein type 10 subunit alpha Ligand A-803467 F... 2 81
Macrophage migration inhibitory factor Inhibitor Benzofuran-2-... 5 67
Sodium channel protein type 10 subunit alpha and Sodium channe... 2 13
Beta-secretase 1 inhibitor SureCN3599637 family 1 0
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 11 4
Sodium channel protein type 10 subunit alpha ligand AGN-PC-09M... 1 7
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 2 4
MAP kinase-activated protein kinase 2 inhibitor 5-(4-cyanophen... 3 8
Histamine H3 receptor ligand N-[[2-[2-[(2R)-2-methylpyrrolidin... 4 1
Sphingosine 1-phosphate receptor 4 ligand AGN-PC-079GSR family 11 7


External ID

Functional Category

Molecule Name

CFAMM00402820 CHEMBL2037204 Bioactive (3E)-5-chloro-3-[[5-[2-fluoro-5-(4-methyl-1,4-diazepane-1-carbonyl)phenyl]furan-2-yl]methylidene]-1H-indol-2-one
CFAMM00402825 CHEMBL2037201 Bioactive (3E)-5-chloro-3-[[5-[3-(1,4-diazepane-1-carbonyl)phenyl]furan-2-yl]methylidene]-1H-indol-2-one
CFAMM00402824 CHEMBL2037200 Bioactive (3E)-5-chloro-3-[[5-[3-(4-methyl-1,4-diazepane-1-carbonyl)phenyl]furan-2-yl]methylidene]-1H-indol-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



88552 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543