CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10562
Family Name Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Protein farnesyltransferase subunit beta inhibitor AGN-PC-0760WA family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00402841 Functional Category Bioactive with Natural Product
Superfamily Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Protein farnesyltransferase subunit beta inhibitor AGN-PC-0760WA Superfamily
Class Class 414

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor Ligand Ramosetron Family 10 219
Insulin-degrading enzyme inhibitor cyclic polypeptide Bacitrac... 30 259
Renin Inhibitor Remikiren Family 100 126
Vascular endothelial growth factor receptor 2 Ligand XL999 Family 11 87
Platelet activating factor, putative Inhibitor ABT-491 Family 22 62
Renin Inhibitor (h-261)boc-his-pro-phe-his-leu(oh)-val-ile-his... 33 41
Renin Inhibitor Sul-pro-phe-n-mehis-lva-ile-amp Family 47 54
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 4
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 11 22
Prolyl endopeptidase inhibitor SureCN8938520 family 2 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 8
Lysosomal Pro-X carboxypeptidase inhibitor N-[(2S)-1-[(2S)-2-(... 1 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 6 3
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 9 3
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-0A9QGC ... 14 0
Delta-type opioid receptor ligand ethyl N-[3-[(R)-[4-[ethyl(me... 2 6
Prothrombin and Cationic trypsin inhibitor (2S)-1-[(2R)-3,3-di... 5 9
Histamine H3 receptor ligand 1-[4-(1H-imidazol-5-ylmethyl)pipe... 1 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 13 1
C-C chemokine receptor type 5 ligand AC1MHRXO family 5 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00402844 CHEMBL380973 Bioactive ethyl 2-[3-[3-(1H-imidazol-5-yl)propyl]-5-methyl-5-naphthalen-1-yl-2,4-dioxoimidazolidin-1-yl]acetate
CFAMM00402843 CHEMBL204787 Bioactive AGN-PC-0760XE
CFAMM00402841 CHEMBL203737 Bioactive AGN-PC-0760WA

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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