CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10563
Family Name Oxytocin receptor ligand (2R)-2-[(2R,5R)-5-(2,3-dihydro-1H-inden-2-yl)-2-(2-methylpropyl)-3,6-dioxopiperazin-1-yl]-2-(6-methoxypyridin-3-yl)-N,N-dimethylacetamide family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00402846 Functional Category Bioactive
Superfamily Chymase and Liver carboxylesterase 1 Binder Superfamily
Class Class 963

Cousin Family NamesSeedsMembers
HIV protease Inhibitor Indinavir Family 36 211
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
Neuronal acetylcholine receptor subunit alpha-4 Ligand TC-5619... 3 61
Cholecystokinin receptor type A Ligand A-71378 Family 77 23
5-hydroxytryptamine receptor 1B Ligand GR55562 Family 3 45
Chymase Inhibitor NK3201 Family 1 0
Mu-type opioid receptor Ligand 6-(4-(2-(benzylamino)ethyl)phen... 3 27
Bifunctional epoxide hydrolase 2 Inhibitor N-benzyl-6-(3,3,3-t... 21 62
C-C chemokine receptor type 5 ligand (2,4-dimethyl-1-oxidopyri... 5 4
Disintegrin and metalloproteinase domain-containing protein 17... 14 9
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 3 28
Gonadotropin-releasing hormone receptor ligand 1-[(2,6-difluor... 6 31
Neuronal acetylcholine receptor subunit alpha-7 ligand 2-[3-cy... 2 5
Renin inhibitor (1R,5S)-N-cyclopropyl-N-[(2-methoxy-3-methylpy... 2 3
Cellular tumor antigen p53 and DNA polymerase beta inhibitor C... 1 15
Voltage-dependent T-type calcium channel subunit alpha-1I liga... 2 6
Histone deacetylase inhibitor (3S,6S,9S,12R)-3-[(2S)-butan-2-y... 1 0
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 4 11
C-C chemokine receptor type 5 ligand N-[(3R)-3-[4-[4-methoxy-N... 13 1
Beta-secretase 1 and Cathepsin D inhibitor N-[(2S,3R)-4-[[(4S)... 34 23
Potassium voltage-gated channel subfamily KQT member 2 ligand ... 3 4
Pol polyprotein inhibitor Palinavir deriv. 13 family 1 0
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 3 7
Melanin-concentrating hormone receptor 1 and Potassium voltage... 2 0
Sodium-dependent serotonin transporter and Neuropeptide Y rece... 1 0
Pol polyprotein inhibitor N-benzyl-2,2-difluoro-4-[[(2S)-3-met... 1 1
Prothrombin inhibitor N-[(2S)-3-(4-aminophenyl)-1-[4-(2-fluoro... 7 4


External ID

Functional Category

Molecule Name

CFAMM00402846 CHEMBL2037486 Bioactive (2R)-2-[(2R,5R)-5-(2,3-dihydro-1H-inden-2-yl)-2-(2-methylpropyl)-3,6-dioxopiperazin-1-yl]-2-(6-methoxypyridin-3-yl)-N,N-dimethylacetamide
CFAMM00402848 CHEMBL2037488 Bioactive (2R)-2-[(2R,5R)-5-(2,3-dihydro-1H-inden-2-yl)-2-(2-methylpropyl)-3,6-dioxopiperazin-1-yl]-N,N-dimethyl-2-(6-oxo-1H-pyridin-3-yl)acetamide
CFAMM00402847 CHEMBL2037487 Bioactive (3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)-1-[(1R)-1-(6-methoxypyridin-3-yl)-2-morpholin-4-yl-2-oxoethyl]-6-(2-methylpropyl)piperazine-2,5-dione

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



109671 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543