CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10569
Family Name Sodium-dependent serotonin transporter and Sodium-dependent dopamine transporter inhibitor SureCN6954322 family
No. of Seeds 9 No. of Other Members 3
Family Centroid CFAMM00008386 Functional Category Bioactive
Superfamily Dipeptidyl peptidase 4 Inhibitor 4-(2,4-dichlorophenyl)-1-tosylpyrrolidin-3-amine Superfamily
Class Class 2453

Cousin Family NamesSeedsMembers
Serotonin re-uptake inhibitor tetralin derivative Sertraline f... 12 118
Dopamine reuptake and Noradrenergic re-uptake Inhibitor Dov 21... 16 89
Sodium-dependent serotonin transporter and Sodium-dependent do... 5 6
Transporter and Sodium-dependent dopamine transporter inhibito... 3 0
Sodium-dependent serotonin transporter and Sodium-dependent do... 2 1
Sodium-dependent serotonin transporter and Sodium-dependent do... 1 0


External ID

Functional Category

Molecule Name

CFAMM00402883 CHEMBL206211 Bioactive (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-7-methylsulfonyl-1,2,3,4-tetrahydronaphthalen-1-amine
CFAMM00402882 CHEMBL204285 Bioactive (5S,8S)-8-(3,4-dichlorophenyl)-5-(methylamino)-5,6,7,8-tetrahydronaphthalene-2-sulfonamide
CFAMM00402880 CHEMBL382241 Bioactive SureCN6249548
CFAMM00402879 CHEMBL381754 Bioactive SureCN6951865

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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