CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10572
Family Name Coagulation factor X inhibitor SureCN8169809 family
No. of Seeds 12 No. of Other Members 18
Family Centroid CFAMM00402907 Functional Category Bioactive
Superfamily Coagulation factor X and Sodium channel protein type 9 subunit alpha Binder Superfamily
Class Class 849

Cousin Family NamesSeedsMembers
Cannabinoid receptor 1 Ligand Rimonabant Family 20 260
Cannabinoid receptor 1 Ligand TM38837 Family 20 15
Coagulation factor X Inhibitor SN429 Family 23 100
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
14-alpha sterol demethylase Inhibitor CP-320626 Family 13 76
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 3 59
Cannabinoid receptor 1 ligand AGN-PC-04YSUM family 7 6
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 8 16
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 2 21
5-hydroxytryptamine receptor 3A ligand SureCN8035577 family 5 4
Inhibitor of nuclear factor kappa-B kinase subunit beta inhibi... 5 19
Inhibitor of nuclear factor kappa-B kinase subunit beta inhibi... 34 4
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor 2-... 18 2
Cannabinoid receptor 1 ligand N-[1-[[(1R)-1-[4-(3-chloroindazo... 10 0
Cannabinoid receptor 1 ligand 5-(4-chlorophenyl)-1-(2,4-dichlo... 2 19
Cannabinoid receptor 1 ligand 5-(4-chlorophenyl)-1-(2,4-dichlo... 1 0
Coagulation factor X inhibitor AGN-PC-0749BY family 5 9
Coagulation factor X and Coagulation factor IX inhibitor pyraz... 11 0
Coagulation factor X and Coagulation factor IX inhibitor pyraz... 6 1
Coagulation factor X and Coagulation factor IX inhibitor pyraz... 2 2
Coagulation factor X and Coagulation factor IX inhibitor pyraz... 3 0
Ribosomal protein S6 kinase alpha-3 inhibitor 1-oxo-N-[1-(pyri... 5 11
Cannabinoid receptor 1 ligand SureCN4819820 family 11 5
Lysosomal Pro-X carboxypeptidase inhibitor [(3S,4R)-1-tert-but... 20 13
Coagulation factor X inhibitor 2-(6-chloronaphthalen-2-yl)-5-m... 2 0
Coagulation factor X inhibitor SureCN8168539 family 3 0
Coagulation factor X inhibitor SureCN8166226 family 3 3
Coagulation factor X inhibitor SureCN8165148 family 4 0
Coagulation factor X inhibitor AGN-PC-0749DA family 3 2
Coagulation factor X inhibitor AGN-PC-02WFR7 family 7 13
Mitogen-activated protein kinase 1 inhibitor Pyrrole Carboxami... 3 12
Coagulation factor X and Prothrombin inhibitor SureCN5819494 f... 5 8
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 8 6
Serine/threonine-protein kinase PLK4 inhibitor (3E)-3-[[3-[(E)... 5 2
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 4 1
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 3 0
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... 9 2
Mitogen-activated protein kinase 8 inhibitor 5-[(6-chloro-1-ox... 5 7
Mitogen-activated protein kinase 8 inhibitor 6-chloro-2-[[5-me... 4 1
Cannabinoid receptor 1 ligand AGN-PC-07R6QU family 4 2
Coagulation factor X inhibitor AGN-PC-046QCP family 2 0
Cannabinoid receptor 1 ligand AGN-PC-07NHJ5 family 9 1
Vasopressin V2 receptor and Vasopressin V1a receptor ligand (2... 1 0
Coagulation factor X inhibitor SureCN5254091 family 5 0
Cannabinoid receptor 1 ligand AGN-PC-07R5TU family 11 0
Cannabinoid receptor 1 ligand AGN-PC-07NHI2 family 4 1
Cannabinoid receptor 1 ligand AGN-PC-07R6O8 family 5 2
Cannabinoid receptor 1 ligand AGN-PC-07RA6C family 21 2
Cannabinoid receptor 1 ligand AGN-PC-07RA3R family 15 0
Cannabinoid receptor 1 ligand SureCN3822127 family 5 0
Cannabinoid receptor 1 ligand 1-(2-chlorophenyl)-5-(4-chloroph... 2 0
Cannabinoid receptor 1 ligand AGN-PC-07R6QS family 5 0
C-C chemokine receptor type 2 ligand methyl (2S)-5-(diaminomet... 3 0
P2X purinoceptor 7 inhibitor SureCN1194877 family 1 6
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 4 0
C-C chemokine receptor type 2 ligand AGN-PC-00ESW1 family 1 0
Apoptosis regulator Bcl-2 and Bcl2-associated agonist of cell ... 3 3
Ketohexokinase inhibitor 3-carbamimidoyl-N-(3-ethyl-1-phenylin... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00402919 CHEMBL20660 Bioactive 2-(6-chloronaphthalen-2-yl)-5-methyl-N-[4-(2-oxopiperidin-1-yl)phenyl]pyrazole-3-carboxamide
CFAMM00402912 CHEMBL20832 Bioactive AGN-PC-0749KZ
CFAMM00402905 CHEMBL20438 Bioactive SureCN8158680
CFAMM00402898 CHEMBL277949 Bioactive AGN-PC-0749JY
CFAMM00402911 CHEMBL20932 Bioactive SureCN8163275
CFAMM00402917 CHEMBL281141 Bioactive SureCN8165043
CFAMM00402897 CHEMBL277657 Bioactive SureCN8170384
CFAMM00402923 CHEMBL21065 Bioactive AGN-PC-0749EI
CFAMM00402922 CHEMBL20391 Bioactive SureCN8163273
CFAMM00402921 CHEMBL20390 Bioactive SureCN8165155
CFAMM00402920 CHEMBL281838 Bioactive SureCN8166444
CFAMM00402907 CHEMBL20918 Bioactive SureCN8169809

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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