CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10585
Family Name Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhibitor AGN-PC-00GOZQ family
No. of Seeds 6 No. of Other Members 5
Family Centroid CFAMM00403014 Functional Category Bioactive
Superfamily Matrix metalloproteinase-9 and 72 kDa type IV collagenase Binder Superfamily 10
Class Class 4794

Cousin Family NamesSeedsMembers
Disintegrin and metalloproteinase domain-containing protein 17... 82 411
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 4-acety... 9 4
Collagenase 3 and 72 kDa type IV collagenase inhibitor AGN-PC-... 3 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 19 11
Disintegrin and metalloproteinase domain-containing protein 17... 5 2
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 0
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 3 0
Matrix metalloproteinase-9 inhibitor N-[1-[(4S)-2,2-dimethyl-1... 10 0
Matrix metalloproteinase-9 inhibitor N-[1-(4,4-dimethyl-2,5-di... 3 3
Disintegrin and metalloproteinase domain-containing protein 17... 12 1
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 1-hydro... 1 1
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 0
72 kDa type IV collagenase inhibitor N-hydroxy-N-[1-[4-[4-(tri... 3 2
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 6 0
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 3 0
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 3 2
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00403014 CHEMBL275654 Bioactive AGN-PC-00GOZQ
CFAMM00403012 CHEMBL311141 Bioactive N-[1-(dimethylsulfamoyl)-3-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylpropan-2-yl]-N-hydroxyformamide
CFAMM00403011 CHEMBL78052 Bioactive N-hydroxy-N-[4-(4-methylsulfonylpiperazin-1-yl)-1-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylbutan-2-yl]formamide
CFAMM00403017 CHEMBL2040991 Bioactive N-[1-[(2S)-4,4-dimethyl-1-methylsulfonylpyrrolidin-2-yl]-2-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylethyl]-N-hydroxyformamide
CFAMM00403016 CHEMBL75567 Bioactive N-[1-(dimethylamino)-3-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylpropan-2-yl]-N-hydroxyformamide
CFAMM00403009 CHEMBL3037894 Bioactive N-hydroxy-N-[(1S)-1-[(2S)-1-methylsulfonylpyrrolidin-2-yl]-2-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylethyl]formamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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