CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10589
Family Name Egl nine homolog 2 and Egl nine homolog 1 inhibitor 4-[4-[1-(6-methoxypyrimidin-4-yl)-8-[(3-methylpyridin-2-yl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-3-yl]phenyl]benzamide family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00402991 Functional Category Bioactive
Superfamily Egl nine homolog 1 and Egl nine homolog 2 Binder Superfamily
Class Class 4519

Cousin Family NamesSeedsMembers
Translocator protein Inhibitor Emapunil Family 7 89
Protein kinase C alpha type and Protein kinase C beta type Inh... 16 86
Class II cytokine receptor Ligand IL-10 Family 7 45
Cholecystokinin receptor type A ligand AGN-PC-0A9S2C family 4 8
Smoothened homolog inhibitor (8aS)-N-[2-(3-cyanophenyl)pyridin... 3 4
Egl nine homolog 2 and Egl nine homolog 1 inhibitor 3-methyl-4... 15 14
Egl nine homolog 2 and Egl nine homolog 1 inhibitor 4-[4-[1-(6... 3 0
Egl nine homolog 2 and Egl nine homolog 1 inhibitor 8-[(3-meth... 7 5
Egl nine homolog 1 and Egl nine homolog 2 inhibitor 1-(6-metho... 4 2
Egl nine homolog 1 and Egl nine homolog 2 inhibitor 3-[4-(3H-b... 1 0
Egl nine homolog 2 and Egl nine homolog 1 inhibitor 4-[4-[1-(6... 10 0
Egl nine homolog 2 and Egl nine homolog 1 inhibitor 8-[(3-meth... 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26834 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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