CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10591
Family Name Egl nine homolog 2 and Egl nine homolog 1 inhibitor 4-[4-[1-(6-methoxypyrimidin-4-yl)-8-[(3-methylpyridin-2-yl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-3-yl]phenyl]benzoic acid family
No. of Seeds 10 No. of Other Members 0
Family Centroid CFAMM00403036 Functional Category Bioactive
Superfamily Egl nine homolog 1 and Egl nine homolog 2 Binder Superfamily
Class Class 4519

Cousin Family NamesSeedsMembers
Cholecystokinin receptor type A ligand AGN-PC-0A9S2C family 4 8
Egl nine homolog 2 and Egl nine homolog 1 inhibitor 3-methyl-4... 15 14
Egl nine homolog 2 and Egl nine homolog 1 inhibitor 4-[4-[1-(6... 3 0
Egl nine homolog 2 and Egl nine homolog 1 inhibitor 4-[4-[1-(6... 5 0
Gastrin/cholecystokinin type B receptor ligand AGN-PC-077L8M f... 24 10


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00403037 CHEMBL2043169 Bioactive 3-[4-[1-(6-methoxypyrimidin-4-yl)-8-[(3-methylpyridin-2-yl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-3-yl]phenyl]benzoic acid
CFAMM00403036 CHEMBL2043168 Bioactive 4-[4-[1-(6-methoxypyrimidin-4-yl)-8-[(3-methylpyridin-2-yl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-3-yl]phenyl]benzoic acid
CFAMM00403035 CHEMBL2043325 Bioactive 4-[4-[1-(6-methoxypyrimidin-4-yl)-8-[(3-methylpyridin-2-yl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-3-yl]phenyl]-3-methylbenzoic acid
CFAMM00403034 CHEMBL2043324 Bioactive 3-fluoro-4-[4-[1-(6-methoxypyrimidin-4-yl)-8-[(3-methylpyridin-2-yl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-3-yl]phenyl]benzoic acid
CFAMM00403039 CHEMBL2043172 Bioactive 2-chloro-4-[4-[1-(6-methoxypyrimidin-4-yl)-8-[(3-methylpyridin-2-yl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-3-yl]phenyl]benzoic acid
CFAMM00403038 CHEMBL2043326 Bioactive 4-[4-[1-(6-methoxypyrimidin-4-yl)-8-[(3-methylpyridin-2-yl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-3-yl]phenyl]-2-methylbenzoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27650 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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