CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10592
Family Name Matrix metalloproteinase-9 inhibitor N-[1-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylethyl]-N-hydroxyformamide family
No. of Seeds 10 No. of Other Members 0
Family Centroid CFAMM00403045 Functional Category Bioactive
Superfamily Matrix metalloproteinase-9 and 72 kDa type IV collagenase Binder Superfamily 10
Class Class 4794

Cousin Family NamesSeedsMembers
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 6 5
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 0
72 kDa type IV collagenase inhibitor N-hydroxy-N-[1-[4-[4-(tri... 3 2
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 6 0


External ID

Functional Category

Molecule Name

CFAMM00403043 CHEMBL2043425 Bioactive N-[1-[(4S)-2,2-diethyl-1,3-dioxolan-4-yl]-2-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylethyl]-N-hydroxyformamide
CFAMM00403042 CHEMBL306050 Bioactive N-hydroxy-N-[(1S)-2-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonyl-1-[(5S)-2,2,5-trimethyl-1,3-dioxolan-4-yl]ethyl]formamide
CFAMM00403041 CHEMBL306301 Bioactive N-[(2S)-1-(2,2-dimethyl-1,3-dioxolan-4-yl)-3-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylpropan-2-yl]-N-hydroxyformamide
CFAMM00403047 CHEMBL306276 Bioactive N-[1-(1,4-dioxaspiro[4.5]decan-8-yl)-2-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylethyl]-N-hydroxyformamide
CFAMM00403040 CHEMBL75114 Bioactive AGN-PC-0A4VNK
CFAMM00403046 CHEMBL2114138 Bioactive N-[(1S)-1-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylethyl]-N-hydroxyformamide
CFAMM00403045 CHEMBL2041307 Bioactive N-[1-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonylethyl]-N-hydroxyformamide
CFAMM00403044 CHEMBL2043424 Bioactive N-hydroxy-N-[2-[4-[4-(trifluoromethoxy)phenoxy]phenyl]sulfonyl-1-[(4S,5S)-2,2,5-trimethyl-1,3-dioxolan-4-yl]ethyl]formamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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