CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10593
Family Name Matrix metalloproteinase-9 inhibitor N-[1-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)-3-[4-[4-(trifluoromethoxy)phenyl]phenyl]sulfonylpropan-2-yl]-N-hydroxyformamide family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00403053 Functional Category Bioactive
Superfamily Matrix metalloproteinase-9 and 72 kDa type IV collagenase Binder Superfamily 11
Class Class 4795

Cousin Family NamesSeedsMembers
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 6 5
72 kDa type IV collagenase inhibitor N-hydroxy-N-[1-[4-[4-(tri... 3 2
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 0
72 kDa type IV collagenase inhibitor AGN-PC-03EJ2S family 8 5


External ID

Functional Category

Molecule Name

CFAMM00403050 CHEMBL76043 Bioactive AGN-PC-074IR6
CFAMM00403048 CHEMBL75618 Bioactive N-[1-[4-(4-butoxyphenyl)phenyl]sulfonyl-3-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)propan-2-yl]-N-hydroxyformamide
CFAMM00403053 CHEMBL2041308 Bioactive N-[1-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)-3-[4-[4-(trifluoromethoxy)phenyl]phenyl]sulfonylpropan-2-yl]-N-hydroxyformamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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