CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10594
Family Name Melanin-concentrating hormone receptor 1 ligand SureCN14265866 family
No. of Seeds 11 No. of Other Members 2
Family Centroid CFAMM00403061 Functional Category Bioactive
Superfamily Melanin-concentrating hormone receptor 1 Binder Superfamily 2
Class Class 3520

Cousin Family NamesSeedsMembers
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-chloro-phenyl)... 5 50
Androgen receptor Ligand YM-175735 Family 30 129
Cannabinoid receptor 1 Ligand 1-(bis(4-chlorophenyl)methyl)-3-... 4 44
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-07ZBI0 family 2 16
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2C8 inhib... 6 5
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 6 12
Melanin-concentrating hormone receptor 1 ligand 1-[(6S)-6-(3-c... 7 18
Melanin-concentrating hormone receptor 1 ligand 3-(3-chloro-4-... 8 24
Melanin-concentrating hormone receptor 1 ligand 3-(3-chloro-4-... 13 6
C-C chemokine receptor type 2 and C-C chemokine receptor type ... 2 8
D(3) dopamine receptor and D(2) dopamine receptor ligand 3-[4-... 4 23
Melanin-concentrating hormone receptor 1 ligand 1-[[4-[4-(3-cy... 14 23
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 6
Melanin-concentrating hormone receptor 1 ligand SureCN3845324 ... 7 4
Melanin-concentrating hormone receptor 1 ligand SureCN14265737... 2 0
C-C chemokine receptor type 1 ligand SureCN3159355 family 7 9
D(3) dopamine receptor and D(2) dopamine receptor ligand RGH-1... 8 0
Melanin-concentrating hormone receptor 1 ligand 3-(3-chloro-4-... 2 1
Melanin-concentrating hormone receptor 1 ligand SureCN13655018... 6 23
Melanin-concentrating hormone receptor 1 ligand AGN-PC-00CYMY ... 1 0
Melanocortin receptor 4 ligand N-[(1S)-1-[2-[4-[(3S,4R)-4-(4-c... 26 13
Melanin-concentrating hormone receptor 1 ligand SureCN13451707... 3 1
Neuropeptide Y receptor type 5 ligand SureCN6214451 family 3 1
Potassium voltage-gated channel subfamily H member 2 and D(3) ... 3 0
Acyl-CoA:cholesterol acyltransferase inhibitor 1-[2,6-di(propa... 7 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00403065 CHEMBL204212 Bioactive 3-(3-chloro-4-fluorophenyl)-1-[(1S,4R,5S)-1-(3,4-difluorophenyl)-4-bicyclo[3.1.0]hexanyl]-1-[3-(4-methylpiperazin-1-yl)propyl]urea
CFAMM00403058 CHEMBL214254 Bioactive N-[3-[(1S,4R,5S)-4-[(3-chloro-4-fluorophenyl)carbamoyl-[3-(4-methylpiperazin-1-yl)propyl]amino]-1-bicyclo[3.1.0]hexanyl]phenyl]cyclopropanecarboxamide
CFAMM00403064 CHEMBL382177 Bioactive 3-(3-chloro-4-fluorophenyl)-1-[(1S,4R,5S)-1-(3-fluorophenyl)-4-bicyclo[3.1.0]hexanyl]-1-[3-(4-methylpiperazin-1-yl)propyl]urea
CFAMM00403057 CHEMBL213187 Bioactive N-[4-[(1S,4R,5S)-4-[(3-chloro-4-fluorophenyl)carbamoyl-[3-(4-methylpiperazin-1-yl)propyl]amino]-1-bicyclo[3.1.0]hexanyl]phenyl]acetamide
CFAMM00403056 CHEMBL383340 Bioactive SureCN14265874
CFAMM00403062 CHEMBL379535 Bioactive 3-(3-chloro-4-fluorophenyl)-1-[(1S,4R,5S)-1-(4-fluorophenyl)-4-bicyclo[3.1.0]hexanyl]-1-[3-(4-methylpiperazin-1-yl)propyl]urea
CFAMM00403055 CHEMBL215338 Bioactive SureCN14265878
CFAMM00403061 CHEMBL381810 Bioactive SureCN14265866
CFAMM00403054 CHEMBL204161 Bioactive 3-(3-chloro-4-fluorophenyl)-1-[(1S,4R,5S)-1-(3,5-difluorophenyl)-4-bicyclo[3.1.0]hexanyl]-1-[3-(4-methylpiperazin-1-yl)propyl]urea
CFAMM00403060 CHEMBL214907 Bioactive 1-[(1S,4R,5S)-1-(4-aminophenyl)-4-bicyclo[3.1.0]hexanyl]-3-(3-chloro-4-fluorophenyl)-1-[3-(4-methylpiperazin-1-yl)propyl]urea
CFAMM00403066 CHEMBL382841 Bioactive 1-[(1S,4R,5S)-1-(3-aminophenyl)-4-bicyclo[3.1.0]hexanyl]-3-(3-chloro-4-fluorophenyl)-1-[3-(4-methylpiperazin-1-yl)propyl]urea

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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