CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10602
Family Name Growth hormone secretagogue receptor type 1 ligand AGN-PC-0760ZV family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00403128 Functional Category Bioactive
Superfamily Growth hormone secretagogue receptor type 1 and cAMP Binder Superfamily
Class Class 857

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Pyrimethamine Family 10 145
Neuropeptide Y receptor type 5 Ligand CGP71683A Family 5 74
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Corticotropin-releasing factor receptor 1 Ligand CRA1000 Family 4 39
Peptide deformylase, mitochondrial Inhibitor 5-phenylsulfanyl-... 5 23
Peptide deformylase, mitochondrial Inhibitor 5-phenethyl-quina... 5 14
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Epidermal growth factor receptor Ligand N4-(3-chlorophenyl)qui... 7 39
Oestrogen receptor Ligand 4-benzyl-2,6-diisobutylamino-pyrimid... 5 37
Prostaglandin G/H synthase 2 Inhibitor GW-637185X Family 27 48
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 22
Sodium-dependent serotonin transporter Inhibitor 6-chloro-2-pi... 5 35
Corticotropin-releasing factor receptor 1 Ligand N-mesityl-6-m... 3 2
Corticotropin-releasing factor receptor 1 ligand 4-N-(2-bromo-... 9 48
Corticotropin-releasing factor receptor 1 ligand N-(2-bromo-4-... 5 0
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 8
Corticotropin-releasing factor receptor 1 ligand AGN-PC-01ZUJC... 2 1
Corticotropin-releasing factor receptor 1 ligand 3-(2-bromo-4-... 13 34
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-07ZB89 family 6 13
Inhibitor of nuclear factor kappa-B kinase subunit beta inhibi... 1 7
Adenosine kinase inhibitor 5-(4-chlorophenyl)-6-[2-(6-morpholi... 8 8
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... 1 0
Histamine H4 receptor ligand 2-[[6-iodo-2-(4-methylpiperazin-1... 4 2
Growth hormone secretagogue receptor type 1 and Dihydrofolate ... 3 6
Corticotropin-releasing factor receptor 1 ligand 9-(2-bromo-4-... 15 3
Corticotropin-releasing factor receptor 1 ligand 9-(2-bromo-4-... 5 2
Corticotropin-releasing factor receptor 1 ligand SureCN8181501... 4 2
Neuropeptide Y receptor type 5 ligand SureCN8898853 family 2 3
Corticotropin-releasing factor receptor 1 ligand AGN-PC-008HTV... 2 1
Dipeptidyl peptidase 4 inhibitor Aminomethylpyrimidine 1ck family 6 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 8
Aurora kinase A and Aurora kinase B inhibitor 2-[[5-chloro-2-[... 3 7
Growth hormone secretagogue receptor type 1 ligand SureCN63605... 5 7
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 2-[4... 5 5
Serine/threonine-protein kinase SMG1 and Serine/threonine-prot... 10 0
Serine/threonine-protein kinase SMG1 and Cyclin-dependent kina... 3 1
Adenosine kinase inhibitor 4-[2-[5-(4-chlorophenyl)-6-piperazi... 3 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor AG... 3 1
Prostaglandin G/H synthase 2 inhibitor 4-N,4-N-diethyl-2-(4-me... 5 1
Dihydrofolate reductase inhibitor WR 158122 family 1 0
Prostaglandin G/H synthase 2 inhibitor 6-ethoxy-2-(4-methylsul... 5 1
Prostaglandin G/H synthase 2 inhibitor 2-(4-methylsulfonylphen... 1 0
Dihydrofolate reductase inhibitor 5-[4-[(3,4-dichlorophenyl)me... 1 0
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 1 0
Growth hormone secretagogue receptor type 1 ligand AGN-PC-00CN... 1 2
Histamine H4 receptor and Histamine H1 receptor ligand 6-chlor... 1 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 7 0
Nitric oxide synthase, brain and Nitric oxide synthase, induci... 2 0
Focal adhesion kinase 1 and Protein-tyrosine kinase 2-beta inh... 1 1
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 3 0
Histamine H4 receptor ligand 2-[[6-chloro-2-(4-methylpiperazin... 7 2
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 1 2
Aurora kinase A and Vascular endothelial growth factor recepto... 1 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand 4-N-[... 16 21


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00403128 CHEMBL204266 Bioactive AGN-PC-0760ZV
CFAMM00403127 CHEMBL383411 Bioactive AGN-PC-009FXJ
CFAMM00403126 CHEMBL206589 Bioactive AGN-PC-00CIIJ
CFAMM00403125 CHEMBL206588 Bioactive AGN-PC-008YFQ

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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