CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10603
Family Name ALK tyrosine kinase receptor and Insulin receptor ligand 2-[[5-chloro-2-[(1-methyl-2-oxo-4,5-dihydro-3H-1-benzazepin-7-yl)amino]pyrimidin-4-yl]amino]-N-methylbenzenesulfonamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00403129 Functional Category Bioactive
Superfamily Insulin receptor and ALK tyrosine kinase receptor Binder Superfamily
Class Class 1334

Cousin Family NamesSeedsMembers
Reverse transcriptase Inhibitor Nevirapine Family 23 640
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
JAK Inhibitor Momelotinib Family 33 83
Bacterial outer membrane Inhibitor HKI-9924129 Family 19 85
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 4 14
Coagulation factor X inhibitor AGN-PC-075AY8 family 28 21
Hepatocyte growth factor receptor and Insulin receptor ligand ... 4 15
ALK tyrosine kinase receptor and Insulin receptor ligand N-[(1... 3 6
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 2 0
Coagulation factor X inhibitor AGN-PC-078Y0S family 7 1


External ID

Functional Category

Molecule Name

CFAMM00403129 CHEMBL2042694 Bioactive 2-[[5-chloro-2-[(1-methyl-2-oxo-4,5-dihydro-3H-1-benzazepin-7-yl)amino]pyrimidin-4-yl]amino]-N-methylbenzenesulfonamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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