CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10605
Family Name Peroxisome proliferator-activated receptor gamma ligand (9aS)-8-acetyl-N-[(4-fluoro-2-methylnaphthalen-1-yl)methyl]-1,7-dihydroxy-3-methoxy-9a-methyl-9-oxodibenzofuran-4-carboxamide family
No. of Seeds 4 No. of Other Members 44
Family Centroid CFAMM00403181 Functional Category Bioactive with Natural Product
Superfamily Acetylcholinesterase and Glucocorticoid receptor Binder Superfamily
Class Class 2356

Cousin Family NamesSeedsMembers
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor Mycophenola... 4 353
Cyclin-dependent kinase 2 Inhibitor Flavopiridol Family 4 124
C-C chemokine receptor type 5 Ligand GW873140 Family 6 78
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 1 42
Cytochrome P450 2D6 and Delta-type opioid receptor Ligand 4-(s... 17 381
cAMP-dependent protein kinase type II-beta regulatory subunit ... 34 81
Plasmepsin-2 Inhibitor PS-662477 Family 7 55
Leukotriene B4 receptor 1 Ligand SC-51146 Family 6 315
Acetylcholinesterase and Cholinesterase Inhibitor 3-[7-(benzyl... 22 303
Beta-2 adrenergic receptor Ligand Gnf-pf-1694 Family 4 70
Protein kinase C gamma type and Protein kinase C alpha type In... 2 1
Estrogen receptor ligand 2-(3-hydroxy-6-oxoxanthen-9-yl)-5-[[4... 1 2
C-C chemokine receptor type 1 and Chemokine (C-C motif) recept... 1 16
Histamine H3 receptor and Sodium-dependent serotonin transport... 2 11
C-C chemokine receptor type 3 ligand N-[(3R)-1-[(6-fluoronapht... 1 4
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 4 3
Inosine-5'-monophosphate dehydrogenase 2 inhibitor (E)-6-(4-hy... 1 10
Acetylcholinesterase inhibitor 4-[(2-methoxyanilino)methyl]-[1... 2 4
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 2 110
Inosine-5'-monophosphate dehydrogenase 2 and Inosine-5'-monoph... 1 14


External ID

Functional Category

Molecule Name

CFAMM00403184 CHEMBL2042814 Bioactive (9aS)-8-acetyl-N-[(2-ethyl-4-fluoronaphthalen-1-yl)methyl]-1,7-dihydroxy-3-methoxy-9a-methyl-9-oxodibenzofuran-4-carboxamide
CFAMM00403181 CHEMBL2042810 Bioactive (9aS)-8-acetyl-N-[(4-fluoro-2-methylnaphthalen-1-yl)methyl]-1,7-dihydroxy-3-methoxy-9a-methyl-9-oxodibenzofuran-4-carboxamide
CFAMM00403139 CHEMBL2042803 Bioactive (9aS)-8-acetyl-N-[(2-ethylnaphthalen-1-yl)methyl]-1,7-dihydroxy-3-methoxy-9a-methyl-9-oxodibenzofuran-4-carboxamide
CFAMM00403144 CHEMBL2042809 Bioactive (9aS)-8-acetyl-N-[(7-chloro-2-methylnaphthalen-1-yl)methyl]-1,7-dihydroxy-3-methoxy-9a-methyl-9-oxodibenzofuran-4-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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