CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10606
Family Name ALK tyrosine kinase receptor and Ribosomal protein S6 kinase alpha-2 ligand (1S,2S,3R,4R)-3-[[5-chloro-2-[[(7S)-4-methoxy-7-morpholin-4-yl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-yl]amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide family
No. of Seeds 6 No. of Other Members 2
Family Centroid CFAMM00403188 Functional Category Bioactive
Superfamily ALK tyrosine kinase receptor and Insulin receptor Binder Superfamily
Class Class 831

Cousin Family NamesSeedsMembers
AP26113 family 16 90
Potassium voltage-gated channel subfamily H member 2 Ligand Be... 22 56
ALK tyrosine kinase receptor and Insulin receptor ligand N-[(1... 3 20
ALK tyrosine kinase receptor and Insulin receptor ligand SureC... 7 1
Calcium/calmodulin-dependent protein kinase kinase 2 and Focal... 3 17
ALK tyrosine kinase receptor ligand CHEMBL1946804 family 3 0
Insulin-like growth factor 1 receptor ligand GSK1220512A family 20 15
ALK tyrosine kinase receptor and Insulin receptor ligand 7-[[5... 4 1
Focal adhesion kinase 1 inhibitor 2-[[2-(2-methoxy-4-morpholin... 2 1
Insulin-like growth factor 1 receptor ligand AGN-PC-050GPS family 7 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00403192 CHEMBL2064663 Bioactive (1S,2S,3R,4R)-3-[[5-chloro-2-[[(7R)-4-methoxy-7-(2-methoxyethylamino)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-yl]amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
CFAMM00403190 CHEMBL2064664 Bioactive (1S,2S,3R,4R)-3-[[5-chloro-2-[[3-methoxy-7-(2-methoxyethylamino)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
CFAMM00403189 CHEMBL2064667 Bioactive (1S,2S,3R,4R)-3-[[5-chloro-2-[(3-methoxy-7-morpholin-4-yl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
CFAMM00403188 CHEMBL2064666 Bioactive (1S,2S,3R,4R)-3-[[5-chloro-2-[[(7S)-4-methoxy-7-morpholin-4-yl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-yl]amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
CFAMM00403187 CHEMBL2064722 Bioactive (1S,2S,3R,4R)-3-[[5-chloro-2-[[4-methoxy-7-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-yl]amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

44593 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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