CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10607
Family Name ALK tyrosine kinase receptor and Insulin receptor ligand 7-[[5-chloro-4-(2-propan-2-ylsulfonylanilino)pyrimidin-2-yl]amino]-1-ethyl-8-methoxy-4,5-dihydro-3H-1-benzazepin-2-one family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00376928 Functional Category Bioactive
Superfamily Prelamin-A/C and Insulin receptor Binder Superfamily 2
Class Class 481

Cousin Family NamesSeedsMembers
AP26113 family 16 90
ALK Inhibitor ASP3026 Family 2 4
Potassium voltage-gated channel subfamily H member 2 Ligand Be... 22 56
ALK tyrosine kinase receptor and Insulin receptor ligand N-[(1... 3 20
ALK tyrosine kinase receptor and Insulin receptor ligand SureC... 7 1
Calcium/calmodulin-dependent protein kinase kinase 2 and Focal... 3 17
ALK tyrosine kinase receptor ligand CHEMBL1946804 family 3 0
Insulin-like growth factor 1 receptor ligand GSK1220512A family 20 15
ALK tyrosine kinase receptor and Ribosomal protein S6 kinase a... 6 2
ALK tyrosine kinase receptor and Insulin receptor ligand cerit... 2 0
Focal adhesion kinase 1 inhibitor 2-[[2-(2-methoxy-4-morpholin... 2 1
Ephrin type-B receptor 4 ligand AGN-PC-077MSC family 4 15


External ID

Functional Category

Molecule Name

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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