CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10625
Family Name NS3 inhibitor SureCN14450642 family
No. of Seeds 4 No. of Other Members 7
Family Centroid CFAMM00403324 Functional Category Bioactive
Superfamily NS3 and Neutrophil elastase Binder Superfamily
Class Class 1043

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor Ligand Felypressin Family 12 820
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
Glutathione S-transferase Inhibitor Praziquantel Family 5 167
Prothrombin Inhibitor Efegatran Family 9 47
Neutrophil elastase Inhibitor FK-706 Family 8 85
Cathepsin F and Cruzipain Inhibitor Benzoyl-arginine-alanine-m... 49 348
Beta-secretase 1 Inhibitor MMI-175 Family 30 137
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
Plasmepsin-1 Inhibitor SC-5003 Family 93 173
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Mu-type opioid receptor and Nociceptin receptor Ligand Nocicep... 35 5
Cathepsin K inhibitor [(3S)-4,4-dimethyl-1-(naphthalene-2-carb... 4 9
Cathepsin K inhibitor (4-phenylphenyl) (3S)-3-[[(3S)-1,2-dioxo... 4 10
Cathepsin K inhibitor [(3S)-4,4-dimethyl-2-oxo-1-(2-phenylethy... 7 9
Cathepsin K inhibitor [(3S)-4,4-dimethyl-2-oxo-1-(phenylcarbam... 3 1
Cathepsin K inhibitor [(3S)-1-(1-benzothiophene-2-carbonyl)-4,... 2 3
Cathepsin K inhibitor [(3S)-1-(benzenesulfonyl)-4,4-dimethylpy... 2 0
Cathepsin K inhibitor [(3R)-4,4-dimethyl-1-phenylpentan-3-yl] ... 7 7
Neutrophil elastase inhibitor benzyl N-[(2S)-1-[(2S)-2-[[(3S)-... 4 0
Chymase and Chymotrypsinogen A inhibitor tert-butyl N-[(2S)-1-... 2 7
Renin and Cathepsin D inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-... 3 4
Cathepsin K and Cathepsin S inhibitor (2,2,4-trimethyl-3-bicyc... 1 0
Cathepsin K and Cathepsin S inhibitor SureCN6197793 family 1 0
NS3 and Neutrophil elastase inhibitor (2S)-3-[(2S)-2-(tert-but... 1 3
NS3 inhibitor 2-methylpropyl N-[(2S)-1-[(3aR,4S,6aR)-4-[[1-[[2... 1 0
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 3 1
Renin and Cathepsin D inhibitor (4S)-5-cyclohexyl-2,2-difluoro... 15 0
Pepsin A and Renin inhibitor N-[(3R)-1-[[(1S)-1-hydroxy-3-[[(2... 1 0
Trypsin-1 and Prothrombin inhibitor tert-butyl N-[2-[(2S)-2-[[... 1 0
NS3 inhibitor tert-butyl N-[(1S)-1-cyclohexyl-2-[(1R,2S,5S)-2-... 1 0
NS3 inhibitor 6-[[(2S)-1-[[(2S)-1-[(2S)-2-[[1-(cyclopropylamin... 2 0
Putative NP ZINC08790318 Family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00403325 CHEMBL208138 Bioactive SureCN13224178
CFAMM00403324 CHEMBL377179 Bioactive SureCN14450642
CFAMM00403330 CHEMBL204521 Bioactive SureCN10139725
CFAMM00403329 CHEMBL206271 Bioactive SureCN14450701

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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