CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10626
Family Name cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-specific 3',5'-cyclic phosphodiesterase 4D inhibitor SureCN4035640 family
No. of Seeds 5 No. of Other Members 2
Family Centroid CFAMM00403336 Functional Category Bioactive
Superfamily Coagulation factor X and cAMP-specific 3',5'-cyclic phosphodiesterase 4B Binder Superfamily
Class Class 8

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Disopyramid... 4 352
Prostaglandin G/H synthase 2 Inhibitor Etoricoxib Family 2 99
D(3) dopamine receptor Ligand SB-277011 Family 13 178
Carbonic anhydrase 2 Inhibitor N-[2-(1h-indol-5-yl)-butyl]-4-s... 12 70
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 8-(3... 4 19
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 8-(3... 4 22
5-hydroxytryptamine receptor 6 Ligand 4-(1h-indol-1-ylsulfonyl... 7 79
Branched-chain-amino-acid aminotransferase, cytosolic Inhibito... 1 2
Transient receptor potential cation channel subfamily V member... 6 23
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Glutamate receptor 1 Ligand Piriqualone Family 8 67
Metabotropic glutamate receptor 5 Ligand 3-m-tolyl-1,5-naphthy... 6 10
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Prostaglandin G/H synthase 2 Inhibitor 2-(4-(methylsulfonyl)ph... 7 33
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 17 14
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 1 0
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 10 2
Muscarinic acetylcholine receptor M2 ligand AGN-PC-0745NK family 2 6
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... 1 36
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 1 0
5-hydroxytryptamine receptor 6 ligand SureCN3411879 family 10 3
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 9 16
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 5 5
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 2 0
Pol polyprotein inhibitor AC1LAHQ9 family 8 15
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 2 3
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 4 0
Cannabinoid receptor 1 ligand N-(cyclobutylmethyl)-3-[[4-(meth... 1 1
Gonadotropin-releasing hormone receptor ligand SureCN7899418 f... 12 4
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 6-(b... 5 5
Coagulation factor X and Trypsin-1 inhibitor SureCN6166035 family 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00403336 CHEMBL208382 Bioactive SureCN4035640
CFAMM00403337 CHEMBL383225 Bioactive SureCN4044064

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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