CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10632
Family Name Cytosolic phospholipase A2 inhibitor AGN-PC-00BH8R family
No. of Seeds 6 No. of Other Members 13
Family Centroid CFAMM00403385 Functional Category Bioactive
Superfamily Prostaglandin D2 receptor and 3-oxo-5-alpha-steroid 4-dehydrogenase 1 Binder Superfamily
Class Class 2976

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Indomethacin Family 6 271
Phospholipase A2, membrane associated Inhibitor Varespladib Fa... 37 190
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 12 197
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 4 42
5-hydroxytryptamine receptor 1A Ligand Sun N4057 Family 2 86
Cannabinoid receptor 2 Ligand JWH-202 Family 9 172
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand WIN-5... 12 52
Vascular endothelial growth factor receptor 1 Ligand Lycogarub... 6 292
DNA-dependent protein kinase catalytic subunit Inhibitor 8-(1h... 3 85
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 3-(furan-3-... 3 44
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 14 214
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Prostaglandin G/H synthase 2 Inhibitor L-761000 Family 8 44
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 22 57
Tyrosine-protein kinase SYK and Low affinity immunoglobulin ep... 1 0
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 11
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 11 391
Phospholipase A2 inhibitor SureCN7046992 family 2 3
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 8 21
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 4 14
Cysteinyl leukotriene receptor 1 ligand AGN-PC-075KCE family 5 33
Cellular tumor antigen p53 inhibitor CHEMBL1395699 family 1 30
Cellular tumor antigen p53 and Lethal(3)malignant brain tumor-... 1 6
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 16
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 15
Histamine H3 receptor ligand SureCN2784306 family 5 3
Cannabinoid receptor 1 ligand 5-cyano-N-(3-hydroxy-2,2-dimethy... 17 4
Coagulation factor X and Trypsin-1 inhibitor AGN-PC-0759OR family 4 7
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 5 12
Prostaglandin D2 receptor and Prostacyclin receptor ligand 2-[... 15 2
Retinoic acid receptor RXR-alpha ligand (E)-3-[3-(3,5-ditert-b... 5 5
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [5-(o... 4 4
Retinoic acid receptor RXR-alpha ligand 6-[(3-butoxy-5,5,8,8-t... 2 2
Prostaglandin D2 receptor and Prostaglandin E2 receptor EP2 su... 2 0
NS5B protein inhibitor AC1O5AET family 3 1
Translocator protein inhibitor (4S)-N,N-diethyl-9-(2-fluoranyl... 9 10
Peroxisome proliferator-activated receptor delta and Peroxisom... 3 17
Serine/threonine-protein kinase pim-2 and cGMP-dependent prote... 8 1
Peroxisome proliferator-activated receptor alpha and Peroxisom... 1 4
Histamine H3 receptor ligand 2-[4-(1-methylpyrrole-2-carbonyl)... 3 4
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 12 0
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 1 5
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 42 20
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-(1-... 3 2
Prostaglandin D2 receptor 2 ligand AGN-PC-00DCHA family 6 10
Potassium voltage-gated channel subfamily H member 2 and 5-hyd... 2 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 4 1
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 3 3
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 7 1
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 18 39
Interstitial collagenase and Matrilysin inhibitor (3S,6R,7S)-N... 2 4
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
CGMP-dependent protein kinase inhibitor AGN-PC-075IHL family 2 8
Peroxisome proliferator-activated receptor alpha and Peroxisom... 6 14
Ras guanyl-releasing protein 3 and Protein kinase C alpha type... 2 6
Cysteinyl leukotriene receptor 2 and Cysteinyl leukotriene rec... 1 6
Cysteinyl leukotriene receptor 1 ligand 2-[2-[5-[[3-[(E)-2-(6,... 1 8
Retinoic acid receptor RXR-alpha and Retinoic acid receptor RX... 1 0
Histamine H1 receptor and Alpha-1B adrenergic receptor ligand ... 1 4
Histamine H1 receptor and Histamine H2 receptor ligand SureCN6... 1 3
Histamine H1 receptor and Histamine H2 receptor ligand SureCN5... 3 6
Fatty-acid amide hydrolase 1 and Cytosolic phospholipase A2 in... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00403380 CHEMBL204618 Bioactive AGN-PC-00E2MZ
CFAMM00403393 CHEMBL484413 Bioactive AGN-PC-071FXT
CFAMM00403392 CHEMBL426665 Bioactive AGN-PC-00CIK1
CFAMM00403385 CHEMBL207977 Bioactive AGN-PC-00BH8R
CFAMM00403397 CHEMBL443834 Bioactive CAY10502
CFAMM00403383 CHEMBL208401 Bioactive SureCN3927580

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48705 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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