CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10636
Family Name Serine/threonine-protein kinase pim-3 and Serine/threonine-protein kinase pim-1 inhibitor (5Z)-5-[[2-[(3S)-3-aminopyrrolidin-1-yl]-3-chlorophenyl]methylidene]-1,3-thiazolidine-2,4-dione family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00403421 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase pim-3 and Serine/threonine-protein kinase pim-1 inhibitor (5Z)-5-[[2-[(3S)-3-aminopyrrolidin-1-yl]-3-chlorophenyl]methylidene]-1,3-thiazolidine-2,4-dione Superfamily
Class Class 1090

Cousin Family NamesSeedsMembers
Amine oxidase [flavin-containing] B Inhibitor L-136662 Family 3 20
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 1 0
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00403422 CHEMBL2046468 Bioactive (5Z)-5-[[2-[(3S)-3-aminopyrrolidin-1-yl]-4-chlorophenyl]methylidene]-1,3-thiazolidine-2,4-dione
CFAMM00403421 CHEMBL2048863 Bioactive (5Z)-5-[[2-[(3S)-3-aminopyrrolidin-1-yl]-3-chlorophenyl]methylidene]-1,3-thiazolidine-2,4-dione
CFAMM00403420 CHEMBL2048866 Bioactive (5Z)-5-[[2-[(3R)-3-aminopiperidin-1-yl]-3-chlorophenyl]methylidene]-1,3-thiazolidine-2,4-dione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27521 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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