CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10640
Family Name Mu-type opioid receptor and Nitric oxide synthase, brain ligand N'-[1-[2-(diethylamino)ethyl]-2-[(4-ethoxyphenyl)methyl]benzimidazol-5-yl]thiophene-2-carboximidamide;hydrochloride family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00295446 Functional Category Bioactive
Superfamily Glucokinase and Coagulation factor X Binder Superfamily
Class Class 1249

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Astemizole Family 7 240
Platelet-derived growth factor receptor Ligand CP-868596 Family 3 91
DNA Binder Bisbenzimide (hoechst 33258) Family 4 159
Serine/threonine-protein kinase Chk2 Inhibitor 5-nitro-2-(4-ph... 6 3
Melanin-concentrating hormone receptor 1 Ligand ADS-103214 Family 3 4
Fatty-acid amide hydrolase 1 Inhibitor BMS-1 Family 5 22
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 10 46
Prostaglandin D2 receptor ligand 3-[2-methoxy-6-[2-(4-methoxyp... 2 12
Survival motor neuron protein inhibitor CHEMBL1379159 family 1 10
Cellular tumor antigen p53 and Prelamin-A/C inhibitor CHEMBL14... 2 11
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 3 21
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 2 0
Tyrosine-protein kinase ITK/TSK and Tyrosine-protein kinase Lc... 2 6
Melanin-concentrating hormone receptor 1 ligand (1S,3S)-1-N-(4... 3 9
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 4 1
Cannabinoid receptor 2 ligand AGN-PC-03LKW5 family 24 5
Metabotropic glutamate receptor 2 ligand 2-[[(1R,5S)-6-[(2,5-d... 2 3
Cannabinoid receptor 2 ligand SureCN14457828 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00403430 CHEMBL518206 Bioactive AGN-PC-078VB9
CFAMM00403431 CHEMBL2048417 Bioactive N'-[3-[2-(diethylamino)ethyl]-2-[(4-ethoxyphenyl)methyl]benzimidazol-5-yl]thiophene-2-carboximidamide;hydrochloride

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26384 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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