CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10664
Family Name Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor [4-(2,3-dihydro-1,4-benzodioxin-6-ylcarbamoylamino)phenyl] sulfamate family
No. of Seeds 2 No. of Other Members 11
Family Centroid CFAMM00403533 Functional Category Bioactive
Superfamily Chymase and Beta-lactamase Binder Superfamily
Class Class 3415

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Neostigmine Family 4 76
Sodium channel protein type 10 subunit alpha and Sodium channe... 1 7
Beta-1 adrenergic receptor Ligand Practolol Family 2 82
Acyl-CoA desaturase Inhibitor Isoxyl Family 5 62
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 3 67
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 11 20
Cannabinoid receptor 1 Ligand N-(4-methoxyphenyl)oleamide Family 4 23
Bifunctional epoxide hydrolase 2 Inhibitor 1-adamantan-1-yl-3-... 12 44
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
Fatty-acid amide hydrolase 1 Inhibitor 2-fluorophenyl 4-(octyl... 15 9
Fatty-acid amide hydrolase 1 Inhibitor Propan-2-one O-4-(hexyl... 12 4
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Fatty-acid amide hydrolase 1 Inhibitor Phenmedipham Family 2 5
Tyrosinase Inhibitor 1-(4-(benzyloxy)phenyl)-3-hydroxyurea Family 9 23
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 3 1
Gastrin/cholecystokinin type B receptor ligand 1-[3-[[2-(3-met... 2 12
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
Gonadotropin-releasing hormone receptor ligand SureCN5756131 f... 5 7
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 6 1
Androgen receptor ligand (2R)-2-ethyl-1-(2,2,2-trifluoroethyl)... 32 6
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 1
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 4 19
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial ... 3 3
Neuropeptide Y receptor type 5 ligand 3-[4-(4-fluorophenoxy)ph... 4 0
Neuropeptide Y receptor type 5 ligand 1-[1-(4-fluorophenyl)pro... 2 8
Protein-S-isoprenylcysteine O-methyltransferase inhibitor N-[2... 1 2
Transient receptor potential cation channel subfamily V member... 2 7
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075HBO ... 2 44
N,N'-bis(3,4-dimethoxyphenyl)-2-(3,3-dimethyl-2,4-dihydroisoqu... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00403527 CHEMBL2178657 Bioactive 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[2-(3-prop-1-en-2-ylphenyl)propan-2-yl]urea
CFAMM00403533 CHEMBL2047842 Bioactive [4-(2,3-dihydro-1,4-benzodioxin-6-ylcarbamoylamino)phenyl] sulfamate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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