CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10667
Family Name Beta-secretase 1 and Cathepsin D inhibitor N-[4-[[(3S,4S,5R)-5-[(3-tert-butylphenyl)methylamino]-4-hydroxy-1,1-dioxothian-3-yl]methyl]-2-ethyl-6-fluorophenyl]acetamide family
No. of Seeds 1 No. of Other Members 12
Family Centroid CFAMM00403549 Functional Category Bioactive
Superfamily Cathepsin D and Beta-secretase 1 Binder Superfamily 6
Class Class 3550

Cousin Family NamesSeedsMembers
Cytochrome P450 3A4 and Beta-secretase 1 inhibitor N-[(2S,3R)-... 2 40
Beta-secretase 1 and Cathepsin B inhibitor SureCN4666465 family 9 4
Sodium-dependent noradrenaline transporter and Sodium-dependen... 12 16
Beta-secretase 1 and Cathepsin D inhibitor (3S,4S,5R)-3-[(4-am... 1 1


External ID

Functional Category

Molecule Name

CFAMM00403549 CHEMBL2047905 Bioactive N-[4-[[(3S,4S,5R)-5-[(3-tert-butylphenyl)methylamino]-4-hydroxy-1,1-dioxothian-3-yl]methyl]-2-ethyl-6-fluorophenyl]acetamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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