CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1068
Family Name Adenosine receptor A1 ligand SureCN10614388 family
No. of Seeds 5 No. of Other Members 1
Family Centroid CFAMM00318947 Functional Category Bioactive
Superfamily Adenosine receptor A1 and Adenosine receptor A2a Binder Superfamily
Class Class 1027

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand be... 4 301
Cannabinoid receptor 1 Ligand CP-945598 Family 18 173
Dipeptidyl peptidase 4 Inhibitor Linagliptin Family 10 81
cAMP-specific 3',5'-cyclic phosphodiesterase 4D Inhibitor Arof... 3 196
Adenosine receptor A1 and Adenosine receptor A2a Ligand 8-phen... 12 213
Adenosine receptor A1 and Adenosine receptor A2b Ligand PSB-11... 34 26
Histamine H3 receptor Ligand SCH79687 Family 11 29
Herpes simplex virus type 1 thymidine kinase Inhibitor 9-(4-hy... 2 13
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Telomerase reverse transcriptase Inhibitor HOE-33258 Family 10 33
Adenosine receptor A2b Ligand CVT-7124 Family 14 64
Adenosine receptor A2a Ligand (e,e)-8-(4-phenylbutadien-1-yl)c... 11 43
Adenosine receptor A1 and Adenosine receptor A2a Ligand OSIP-3... 4 31
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SCH-577... 9 29
Herpes simplex virus type 1 thymidine kinase Inhibitor N2-(3-t... 1 2
Cannabinoid receptor 1 Ligand 1-(4-chlorophenyl)-2-(2,4-dichlo... 18 41
Poly [ADP-ribose] polymerase 1 inhibitor 2-(3-chlorophenyl)-1H... 4 38
Adenosine receptor A1 ligand 8-(2-amino-4-nitrophenyl)-1,3-dim... 1 0
Adenosine receptor A1 and Adenosine receptor A2b ligand 3-meth... 7 19
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 2 1
Dipeptidyl peptidase 4 inhibitor AGN-PC-046QKE family 3 5
Histamine H4 receptor ligand SureCN602132 family 1 8
Dipeptidyl peptidase 8 and Dipeptidyl peptidase 4 inhibitor Su... 5 13
Melanin-concentrating hormone receptor 1 and Potassium voltage... 8 27
Inositol monophosphatase 1 and 15-hydroxyprostaglandin dehydro... 1 0
Adenosine receptor A3 and Adenosine receptor A1 ligand (8R)-8-... 4 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 18
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QM1E family 8 15
Adenosine receptor A2a and Adenosine receptor A2b ligand SureC... 2 2
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 6 14
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 3 13
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 10 14
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 8
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 1 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 0
Prostaglandin E synthase and Cytochrome P450 2C9 inhibitor 7-b... 1 7
Adenosine receptor A2b and Adenosine receptor A2a ligand N-(4-... 2 14
Vascular endothelial growth factor receptor 2 ligand (3Z)-6-fl... 4 3
Platelet-derived growth factor receptor beta and Vascular endo... 5 12
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 6 5
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 5 0
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-(6-chloro... 2 0
Prostaglandin E synthase inhibitor 2-(2-chloro-6-fluorophenyl)... 9 1
Adenosine receptor A2b ligand N-(4-chlorophenyl)-2-[(5Z)-5-(2,... 1 2
Adenosine receptor A1 ligand 3-(4-Aminophenethyl)-8-(3-noradam... 1 0
Gonadotropin-releasing hormone receptor and 5-hydroxytryptamin... 2 0
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 2 0
Platelet-derived growth factor receptor beta and Fibroblast gr... 10 0
Adenosine receptor A2b ligand N-[(3Z)-3-(2,6-dioxo-1,3-dipropy... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00318951 CHEMBL11410 Bioactive SureCN10614219
CFAMM00318949 CHEMBL268964 Bioactive SureCN10614807
CFAMM00318948 CHEMBL276603 Bioactive 8-(2-amino-4-chlorophenyl)-3-methyl-1-prop-2-enyl-7H-purine-2,6-dione
CFAMM00318947 CHEMBL10995 Bioactive SureCN10614388

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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