CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10694
Family Name Glycogen synthase kinase-3 beta inhibitor 2-(furan-3-yl)-N-[2-[4-(methanesulfonamido)phenyl]ethyl]-1H-imidazo[4,5-b]pyridine-7-carboxamide family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00403781 Functional Category Bioactive
Superfamily Mu-type opioid receptor and Adenosine receptor A1 Binder Superfamily
Class Class 3086

Cousin Family NamesSeedsMembers
Adenosine receptor A2a Ligand BIIB014 Family 26 92
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 1 6
Aurora kinase A and Potassium voltage-gated channel subfamily ... 8 7
Mu-type opioid receptor ligand AGN-PC-075GEP family 1 2
Vascular endothelial growth factor receptor 1 and Receptor-typ... 2 11
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 7 3
G1/S-specific cyclin-E1 and Cyclin-dependent kinase 2 inhibito... 1 4
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 1
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 15 1


External ID

Functional Category

Molecule Name

CFAMM00403776 CHEMBL2048663 Bioactive N-[2-[4-(ethylsulfonylamino)phenyl]ethyl]-2-(furan-3-yl)-1H-imidazo[4,5-b]pyridine-7-carboxamide
CFAMM00403781 CHEMBL2048670 Bioactive 2-(furan-3-yl)-N-[2-[4-(methanesulfonamido)phenyl]ethyl]-1H-imidazo[4,5-b]pyridine-7-carboxamide
CFAMM00403780 CHEMBL2048673 Bioactive N-[2-(2-chloropyridin-3-yl)ethyl]-2-(furan-3-yl)-1H-imidazo[4,5-b]pyridine-7-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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