CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10703
Family Name Receptor tyrosine-protein kinase erbB-2 and Epidermal growth factor receptor ligand N-[2-[4-[4-(1,2-benzothiazol-4-yloxy)-3-chloroanilino]pyrrolo[3,2-d]pyrimidin-5-yl]ethyl]acetamide family
No. of Seeds 9 No. of Other Members 3
Family Centroid CFAMM00403818 Functional Category Bioactive
Superfamily Epidermal growth factor receptor and Receptor tyrosine-protein kinase erbB-2 Inhibitor Lapatinib Superfamily
Class Class 481

Cousin Family NamesSeedsMembers
Epidermal growth factor receptor and Receptor tyrosine-protein... 9 65
Receptor tyrosine-protein kinase erbB-2 Inhibitor TAK-285 Family 16 124
Varlitinib family 2 8
Vascular endothelial growth factor receptor 2 and Fibroblast g... 10 3
Epidermal growth factor receptor and Mitogen-activated protein... 5 19
Epidermal growth factor receptor and Receptor tyrosine-protein... 3 2
Epidermal growth factor receptor and Receptor tyrosine-protein... 6 9
Receptor tyrosine-protein kinase erbB-2 ligand N-[3-chloro-4-(... 4 3
Receptor tyrosine-protein kinase erbB-2 ligand 2-[2-[4-[3-chlo... 4 5
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 3 0
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 3 0
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 2 0
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 4 24
Epidermal growth factor receptor and Receptor tyrosine-protein... 6 0
Epidermal growth factor receptor and Receptor tyrosine-protein... 5 1
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00403813 CHEMBL2048911 Bioactive (2S)-N-[2-[4-[4-(1,2-benzothiazol-4-yloxy)-3-chloroanilino]pyrrolo[3,2-d]pyrimidin-5-yl]ethyl]pyrrolidine-2-carboxamide;hydrochloride
CFAMM00403812 CHEMBL2048910 Bioactive N-[2-[4-[4-(1,2-benzothiazol-4-yloxy)-3-chloroanilino]pyrrolo[3,2-d]pyrimidin-5-yl]ethyl]-2,2-dimethylpropanamide;methanesulfonic acid
CFAMM00403818 CHEMBL2048906 Bioactive N-[2-[4-[4-(1,2-benzothiazol-4-yloxy)-3-chloroanilino]pyrrolo[3,2-d]pyrimidin-5-yl]ethyl]acetamide
CFAMM00403811 CHEMBL2048912 Bioactive 2-amino-N-[2-[4-[4-(1,2-benzothiazol-4-yloxy)-3-chloroanilino]pyrrolo[3,2-d]pyrimidin-5-yl]ethyl]-2-methylpropanamide
CFAMM00403817 CHEMBL2048907 Bioactive N-[2-[4-[4-(1,2-benzothiazol-4-yloxy)-3-chloroanilino]pyrrolo[3,2-d]pyrimidin-5-yl]ethyl]-2-hydroxy-2-methylpropanamide;methanesulfonic acid
CFAMM00403816 CHEMBL2048905 Bioactive 2-[4-[4-(1,2-benzothiazol-4-yloxy)-3-chloroanilino]pyrrolo[3,2-d]pyrimidin-5-yl]ethanol
CFAMM00403809 CHEMBL2048909 Bioactive N-[2-[4-[4-(1,2-benzothiazol-4-yloxy)-3-chloroanilino]pyrrolo[3,2-d]pyrimidin-5-yl]ethyl]-2-methyl-2-methylsulfonylpropanamide
CFAMM00403815 CHEMBL2048908 Bioactive N-[2-[4-[4-(1,2-benzothiazol-4-yloxy)-3-chloroanilino]pyrrolo[3,2-d]pyrimidin-5-yl]ethyl]-3-hydroxy-2,2-dimethylpropanamide
CFAMM00403814 CHEMBL2048798 Bioactive 2-[4-[4-(1-benzothiophen-4-yloxy)-3-chloroanilino]pyrrolo[3,2-d]pyrimidin-5-yl]ethanol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27634 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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