CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10705
Family Name Melanin-concentrating hormone receptor 1 ligand 3-[4-fluoro-3-(trifluoromethyl)phenyl]-1-[(1S,4R,5S)-1-(3-methoxyphenyl)-4-bicyclo[3.1.0]hexanyl]-1-[3-(4-methylpiperazin-1-yl)propyl]urea family
No. of Seeds 3 No. of Other Members 7
Family Centroid CFAMM00403831 Functional Category Bioactive
Superfamily Melanin-concentrating hormone receptor 1 Binder Superfamily 7
Class Class 4801

Cousin Family NamesSeedsMembers
Substance-K receptor Ligand MEN-14933 Family 13 154
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 5 13
Transient receptor potential cation channel subfamily V member... 3 15
Substance-P receptor ligand (2S,4S)-1-N-(3-chlorophenyl)-2-N-[... 5 2
Gonadotropin-releasing hormone receptor ligand SureCN5756131 f... 5 7
Neuropeptide Y receptor type 5 ligand AGN-PC-01NRZ6 family 3 6
Sterol O-acyltransferase 1 inhibitor SureCN6152927 family 7 3
C-C chemokine receptor type 3 ligand SureCN6700764 family 2 2
Melanin-concentrating hormone receptor 1 ligand SureCN13918015... 4 0
D(2) dopamine receptor and D(3) dopamine receptor ligand 1-(3-... 2 0


External ID

Functional Category

Molecule Name

CFAMM00403826 CHEMBL210155 Bioactive 3-(3-chloro-4-fluorophenyl)-1-[(1S,4R,5S)-1-(3-methoxyphenyl)-4-bicyclo[3.1.0]hexanyl]-1-[3-(4-methylpiperazin-1-yl)propyl]urea
CFAMM00403831 CHEMBL206248 Bioactive 3-[4-fluoro-3-(trifluoromethyl)phenyl]-1-[(1S,4R,5S)-1-(3-methoxyphenyl)-4-bicyclo[3.1.0]hexanyl]-1-[3-(4-methylpiperazin-1-yl)propyl]urea
CFAMM00403829 CHEMBL204881 Bioactive 3-[4-fluoro-3-(trifluoromethyl)phenyl]-1-[(1S,4R,5S)-1-(4-methoxyphenyl)-4-bicyclo[3.1.0]hexanyl]-1-[3-(4-methylpiperazin-1-yl)propyl]urea

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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