CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10710
Family Name Serine/threonine-protein kinase pim-1 and Serine/threonine-protein kinase pim-3 inhibitor (5Z)-5-[[2-[(3R)-3-aminopiperidin-1-yl]-3-ethoxyphenyl]methylidene]-1,3-thiazolidine-2,4-dione family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00403854 Functional Category Bioactive
Superfamily Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform and Retinal dehydrogenase 1 Binder Superfamily
Class Class 490

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 6 23
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Substance-P receptor ligand N-[1-[acetyl-[(2-methoxyphenyl)met... 3 9
D(3) dopamine receptor and D(2) dopamine receptor ligand (E)-3... 2 3
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 12 10
D(3) dopamine receptor and D(2) dopamine receptor ligand (E)-N... 2 2
D(4) dopamine receptor and D(3) dopamine receptor ligand SureC... 5 0
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00403854 CHEMBL2048869 Bioactive (5Z)-5-[[2-[(3R)-3-aminopiperidin-1-yl]-3-ethoxyphenyl]methylidene]-1,3-thiazolidine-2,4-dione
CFAMM00403853 CHEMBL2048868 Bioactive (5Z)-5-[[2-[(3R)-3-aminopiperidin-1-yl]-3-methoxyphenyl]methylidene]-1,3-thiazolidine-2,4-dione
CFAMM00403852 CHEMBL2048870 Bioactive (5Z)-5-[[2-[(3R)-3-aminopiperidin-1-yl]-3-(2-methylpropoxy)phenyl]methylidene]-1,3-thiazolidine-2,4-dione
CFAMM00403851 CHEMBL2048871 Bioactive (5Z)-5-[[2-[(3R)-3-aminopiperidin-1-yl]-3-propan-2-yloxyphenyl]methylidene]-1,3-thiazolidine-2,4-dione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27264 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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