CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10718
Family Name Furin inhibitor phenyl 2-[[(2S)-1-[[(2S)-1-[[(2S)-1-(4-carbamimidoylanilino)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]acetate family
No. of Seeds 2 No. of Other Members 5
Family Centroid CFAMM00403889 Functional Category Bioactive
Superfamily Furin and Prothrombin Binder Superfamily
Class Class 4605

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Substance-K receptor Ligand MEN-14933 Family 13 154
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Tyrosinase Inhibitor 1-(4-(benzyloxy)phenyl)-3-hydroxyurea Family 9 23
Substance-P receptor ligand (2S,4S)-1-N-(3-chlorophenyl)-2-N-[... 5 2
Renin and Cytochrome P450 3A4 inhibitor SureCN6719989 family 2 0
Neprilysin and Angiotensin-converting enzyme inhibitor 2-[(3S)... 5 6
Histone deacetylase 8 and Histone deacetylase 6 inhibitor (3S)... 4 16
(2S)-4-methylsulfanyl-2-[[3-(2-oxochromen-3-yl)phenyl]carbamoy... 5 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00403890 CHEMBL400163 Bioactive (2R)-2-[[(2S)-1-[[(2S)-1-anilino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-(4-ethoxyphenyl)-1-oxobutan-2-yl]amino]propanoic acid
CFAMM00403889 CHEMBL2049152 Bioactive phenyl 2-[[(2S)-1-[[(2S)-1-[[(2S)-1-(4-carbamimidoylanilino)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]acetate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27425 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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