CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10719
Family Name Furin inhibitor N-[(2S)-1-[[(2S)-1-[[(2S)-1-(4-carbamimidoylanilino)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]decanamide family
No. of Seeds 3 No. of Other Members 16
Family Centroid CFAMM00403904 Functional Category Bioactive
Superfamily Furin and Trypsin-1 Binder Superfamily
Class Class 2794

Cousin Family NamesSeedsMembers
Prothrombin Inhibitor Ximelagatran Family 5 48
Neuropeptide Y receptor type 1 Ligand BIBO3304 Family 4 69
Integrin alpha-4 Inhibitor BIO-1211 Family 16 83
Prothrombin Inhibitor LB30812 Family 12 36
Prothrombin Inhibitor D-leucyl-n-(4-carbamimidoylbenzyl)-l-pro... 13 44
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 9 19
Cholecystokinin receptor type A Ligand L-708474 Family 14 82
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 12 4
Melanocortin receptor 4 and Melanocyte-stimulating hormone rec... 3 10
Prothrombin and Suppressor of tumorigenicity 14 protein inhibi... 5 8
ALK tyrosine kinase receptor ligand 4-fluoro-N-[6-(piperidin-1... 10 7
Proteinase-activated receptor 1 ligand 2-[[2-[[2-[acetyl-[(E)-... 6 15
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-037CNR f... 5 8
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 11 4
Tryptase alpha/beta-1 and Tryptase delta inhibitor SureCN75047... 4 2
Collagenase 3 and Interstitial collagenase inhibitor (2R,3S)-N... 1 0
Coagulation factor VII and Prothrombin inhibitor 2-[(4-carbami... 1 2
Coagulation factor VII and Prothrombin inhibitor 2-[(4-carbami... 2 1
Coagulation factor VII inhibitor AGN-PC-0752PN family 1 1
Coagulation factor VII and Prothrombin inhibitor AGN-PC-0752NM... 2 3


External ID

Functional Category

Molecule Name

CFAMM00403906 CHEMBL2049154 Bioactive (2S)-2-acetamido-N-[(2S)-1-[[(2S)-1-(4-carbamimidoylanilino)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-5-(diaminomethylideneamino)pentanamide
CFAMM00403905 CHEMBL2049155 Bioactive N-[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-(4-carbamimidoylanilino)-1-oxohexan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]decanamide
CFAMM00403904 CHEMBL2049153 Bioactive N-[(2S)-1-[[(2S)-1-[[(2S)-1-(4-carbamimidoylanilino)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]decanamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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