CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10723
Family Name Vascular endothelial growth factor receptor 2 and Vascular endothelial growth factor receptor 1 ligand SureCN3840360 family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00192226 Functional Category Bioactive
Superfamily Thymidylate synthase and DNA polymerase beta Binder Superfamily
Class Class 931

Cousin Family NamesSeedsMembers
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 13
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
Tyrosine kinase Inhibitor PKI166 Family 17 198
Glucan synthesis regulatory protein Inhibitor Pyridobenzimidaz... 2 12
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 9 Inhibi... 10 35
Adenosine receptor A1 and Adenosine receptor A3 Ligand 2-(4-me... 3 23
Glycogen synthase kinase-3 beta and Mitogen-activated protein ... 8 8
D(4) dopamine receptor Ligand A-425444 Family 2 10
Indoleamine 2,3-dioxygenase 1 Inhibitor 2-(1h-imidazol-4-yl)be... 2 6
Serine/threonine-protein kinase mTOR Inhibitor (4-(6-morpholin... 2 11
Platelet-derived growth factor receptor alpha and Platelet-der... 3 18
Reverse transcriptase Inhibitor UK-129485 Family 23 221
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 13 15
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SK&F-96... 5 83
Adenosine receptor A1 and Adenosine receptor A2a ligand NSC658... 8 54
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 6 35
Serine/threonine-protein kinase B-raf inhibitor SureCN1015955 ... 17 18
Serine/threonine-protein kinase B-raf inhibitor 3-[7-[4-[[(3R)... 6 7
Proto-oncogene tyrosine-protein kinase Src and Cyclin-dependen... 2 1
Tyrosine-protein kinase Lck inhibitor AGN-PC-073GX8 family 12 1
Purine nucleoside phosphorylase inhibitor 7-[(3R,4S,5R)-3,4-di... 10 34
Purine nucleoside phosphorylase inhibitor 2-amino-7-[[(2S,4R)-... 5 0
Adenosine receptor A3 and Adenosine receptor A2a ligand 4-(5-b... 2 5
Survival motor neuron protein and Muscleblind-like protein 1 i... 1 16
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 6 13
Purine nucleoside phosphorylase inhibitor 2-amino-6-benzyl-1,7... 3 2
Neuropeptide Y receptor type 5 ligand 3-[2-[6-[2-[(2-methylpro... 1 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 2 4
Proto-oncogene tyrosine-protein kinase Src and Epidermal growt... 9 9
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 6 12
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 17
Insulin-like growth factor 1 receptor ligand 3qqu family 2 12
Tyrosine-protein kinase Lck and Proto-oncogene tyrosine-protei... 11 2
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 2 3
Hepatocyte growth factor receptor ligand 4-[(6-phenyl-[1,2,4]t... 3 6
Poly [ADP-ribose] polymerase 1 inhibitor 4-[1-[3-(4-oxo-1H-qui... 1 3
Histamine H1 receptor and Histamine H4 receptor ligand 1H-benz... 2 7
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 1 6
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 5 7
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 1 3
Interleukin-1 receptor-associated kinase 4 and Interleukin-1 r... 4 0
Estrogen receptor beta and Estrogen receptor ligand SureCN6442... 1 2
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 4 11
Serine/threonine-protein kinase Chk1 inhibitor SureCN6387344 f... 6 11
Tyrosine-protein kinase Lck inhibitor AGN-PC-0762WF family 2 0
Lysine--tRNA ligase inhibitor 4-[[[2-(2-piperazin-1-ylpyridin-... 2 1
Serine/threonine-protein kinase Chk1 inhibitor 6-chloro-3-(1,3... 4 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 18 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 1
Tyrosine-protein kinase Lck inhibitor 3-[[2-(benzimidazol-1-yl... 2 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 5
Protein kinase C theta type and Protein kinase C delta type in... 2 1
Histone-arginine methyltransferase CARM1 inhibitor AGN-PC-00HE... 4 4
Tyrosine-protein kinase TXK and Tyrosine-protein kinase Lyn in... 1 1
Vascular endothelial growth factor receptor 2 and Vascular end... 1 1
Purine nucleoside phosphorylase inhibitor SureCN6345422 family 9 11
Purine nucleoside phosphorylase inhibitor (3s)-3-(2-amino-4-hy... 2 0
Cyclin-dependent kinase 1 inhibitor AGN-PC-075VQQ family 2 0
G2/mitotic-specific cyclin-B2 and Cyclin-dependent kinase 1 in... 2 1
Vascular endothelial growth factor receptor 2 ligand pyrimidin... 2 2
Epidermal growth factor receptor ligand Pyrido[3,4-d]pyrimidin... 3 1
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 7 6
Purine nucleoside phosphorylase inhibitor SureCN6353628 family 2 0
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-04WWHE family 2 0
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-04WVYY family 1 0
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 5 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

25231 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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