CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10724
Family Name 72 kDa type IV collagenase and Matrix metalloproteinase-9 inhibitor 4-(1,3-dioxoisoindol-2-yl)-2-[4-(4-methylphenyl)phenyl]sulfonylbutanoic acid family
No. of Seeds 12 No. of Other Members 5
Family Centroid CFAMM00403936 Functional Category Bioactive
Superfamily 72 kDa type IV collagenase and Matrix metalloproteinase-9 Binder Superfamily
Class Class 3514

Cousin Family NamesSeedsMembers
Carbonic anhydrase 2 Inhibitor N-benzyl-4-sulfamoyl-benzamide ... 12 44
Farnesyltransferase beta subunit, putative and Protein farnesy... 24 82
72 kDa type IV collagenase and Stromelysin-1 inhibitor (1R,2R,... 1 8
Replication protein E1 inhibitor AC1LAK2U family 3 10
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 4 1
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2J2 inhib... 5 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00403941 CHEMBL383193 Bioactive AGN-PC-0762AC
CFAMM00403947 CHEMBL210517 Bioactive 4-(1,3-dioxoisoindol-2-yl)-2-[4-[2-(4-methylphenyl)ethynyl]phenyl]sulfonylbutanoic acid
CFAMM00403940 CHEMBL207026 Bioactive AGN-PC-0762BL
CFAMM00403946 CHEMBL211036 Bioactive 4-(1,3-dioxoisoindol-2-yl)-2-[4-[2-(4-propylphenyl)ethynyl]phenyl]sulfanylbutanoic acid
CFAMM00403944 CHEMBL204987 Bioactive 4-(1,3-dioxoisoindol-2-yl)-2-[4-[2-(4-methylphenyl)ethynyl]phenyl]sulfinylbutanoic acid
CFAMM00403937 CHEMBL208966 Bioactive 2-[4-(4-cyanophenyl)phenyl]sulfonyl-4-(1,3-dioxoisoindol-2-yl)butanoic acid
CFAMM00403943 CHEMBL379220 Bioactive 4-(1,3-dioxoisoindol-2-yl)-2-[4-[2-(4-ethylphenyl)ethynyl]phenyl]sulfanylbutanoic acid
CFAMM00403949 CHEMBL208749 Bioactive AGN-PC-0762BG
CFAMM00403936 CHEMBL446702 Bioactive 4-(1,3-dioxoisoindol-2-yl)-2-[4-(4-methylphenyl)phenyl]sulfonylbutanoic acid
CFAMM00403942 CHEMBL209165 Bioactive 4-(1,3-dioxoisoindol-2-yl)-2-[4-(4-methylsulfanylphenyl)phenyl]sulfonylbutanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27256 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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