CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10738
Family Name Melanocortin receptor 4 ligand 2-[2-(5-bromo-2-methoxyphenyl)ethyl]-3-fluoro-N-[N'-(4-piperidin-1-ylbutyl)carbamimidoyl]benzamide family
No. of Seeds 6 No. of Other Members 12
Family Centroid CFAMM00404070 Functional Category Bioactive
Superfamily D(2) dopamine receptor Ligand Remoxipride Superfamily
Class Class 35

Cousin Family NamesSeedsMembers
D(2) dopamine receptor Ligand Epidepride Family 31 66
D(2) dopamine receptor and D(3) dopamine receptor ligand 5-bro... 3 11
Sigma non-opioid intracellular receptor 1 and D(3) dopamine re... 26 8
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 1 0


External ID

Functional Category

Molecule Name

CFAMM00404062 CHEMBL205594 Bioactive 2-[2-(5-bromo-2-methoxyphenyl)ethyl]-N-[N'-[(1-ethylpiperidin-4-yl)methyl]carbamimidoyl]-3-fluorobenzamide
CFAMM00404075 CHEMBL207946 Bioactive SureCN3090271
CFAMM00404061 CHEMBL205468 Bioactive SureCN3089287
CFAMM00404073 CHEMBL380854 Bioactive N-[N'-[4-[benzyl(methyl)amino]butyl]carbamimidoyl]-2-[2-(5-bromo-2-methoxyphenyl)ethyl]-3-fluorobenzamide
CFAMM00404064 CHEMBL383117 Bioactive 2-[2-(5-bromo-2-methoxyphenyl)ethyl]-3-chloro-N-[N'-[5-(diethylamino)pentan-2-yl]carbamimidoyl]benzamide
CFAMM00404070 CHEMBL205996 Bioactive 2-[2-(5-bromo-2-methoxyphenyl)ethyl]-3-fluoro-N-[N'-(4-piperidin-1-ylbutyl)carbamimidoyl]benzamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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