CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10740
Family Name Growth hormone secretagogue receptor type 1 ligand AGN-PC-0074FT family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00404080 Functional Category Bioactive
Superfamily Cannabinoid receptor 2 and RAC-beta serine/threonine-protein kinase Binder Superfamily
Class Class 4724

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 15 457
Receptor tyrosine-protein kinase erbB-2 Inhibitor CP-724714 Fa... 4 180
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
SB1518 family 7 103
GDC-0349 family 44 77
JAK Inhibitor Momelotinib Family 33 83
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Mitogen-activated protein kinase 14 and Tyrosine-protein kinas... 3 9
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Serine/threonine-protein kinase mTOR Inhibitor 4-(2-(1h-indol-... 2 15
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-07ZB89 family 6 13
Adenosine kinase inhibitor 5-(4-chlorophenyl)-6-[2-(6-morpholi... 8 8
Mitogen-activated protein kinase 14 inhibitor AGN-PC-03XQYG fa... 7 1
Prostaglandin D2 receptor ligand 2-[3-[2-methoxy-6-[2-(4-metho... 4 12
Insulin-like growth factor 1 receptor ligand AGN-PC-09QIDN family 1 3
Tyrosine-protein kinase Lck and Proto-oncogene tyrosine-protei... 11 2
Serine/threonine-protein kinase mTOR inhibitor SureCN2707225 f... 29 4
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 9 10
Transient receptor potential cation channel subfamily V member... 4 0
Growth hormone secretagogue receptor type 1 ligand SureCN63605... 5 7
Growth hormone secretagogue receptor type 1 ligand SureCN62436... 8 6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 1
Adenosine kinase inhibitor 4-[2-[5-(4-chlorophenyl)-6-piperazi... 3 1
Substance-P receptor and Sodium-dependent serotonin transporte... 11 4
Tyrosine-protein kinase ITK/TSK and Aurora kinase B inhibitor ... 1 1
Transient receptor potential cation channel subfamily V member... 5 1
Adenosine kinase inhibitor SureCN8248615 family 2 3
Growth hormone secretagogue receptor type 1 ligand AGN-PC-00CN... 1 2
Cannabinoid receptor 2 ligand SureCN1626177 family 1 3
Receptor-type tyrosine-protein kinase FLT3 and Non-receptor ty... 3 3
Vascular endothelial growth factor receptor 2 and Cyclin-depen... 1 1
Delta-type opioid receptor ligand SureCN5311914 family 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00404081 CHEMBL456778 Bioactive 2-(phenylmethoxymethyl)-N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)pyridin-2-yl]quinazolin-4-amine
CFAMM00404080 CHEMBL205521 Bioactive AGN-PC-0074FT

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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