CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1075
Family Name Adenosine receptor A2a ligand SureCN6867940 family
No. of Seeds 13 No. of Other Members 13
Family Centroid CFAMM00319080 Functional Category Bioactive
Superfamily Adenosine receptor A2a and Adenosine receptor A1 Binder Superfamily 3
Class Class 1038

Cousin Family NamesSeedsMembers
Metabotropic glutamate receptor 1 Ligand PF-1913539 Family 130 817
Adenosine receptor A2a Ligand BIIB014 Family 26 92
Serine/threonine-protein kinase mTOR Inhibitor INK128 Family 2 15
Adenosine receptor A1 and Adenosine receptor A2a Ligand CGS-15... 24 47
Adenosine receptor A1 and Adenosine receptor A2a Ligand ZM-241... 2 5
Mitogen-activated protein kinase 14 Inhibitor CP-808844 Family 39 43
Adenosine receptor A1 and Adenosine receptor A2a Ligand 4-(fur... 7 15
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 1 0
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 11 0
Adenosine receptor A3 and Adenosine receptor A2a ligand AGN-PC... 8 0
Neuropeptide Y receptor type 5 ligand SureCN5771669 family 2 3
Prelamin-A/C and Prothrombin inhibitor (3-Furan-2-yl-5-methyls... 2 1
Adenosine receptor A3 and Adenosine receptor A2b ligand CHEMBL... 5 0
Survival motor neuron protein and Neuropeptide S receptor liga... 1 2
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 2 1
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 5 8
Adenosine receptor A2a ligand 5-N-[[(2R)-1-[(2-chloro-3,6-difl... 7 9
Adenosine receptor A2a ligand 5-[[[(2R)-1-[(2-chloropyridin-4-... 5 0
Adenosine receptor A2a ligand 2-(furan-2-yl)-7-[3-[(4-phenylpi... 11 2
Fatty-acid amide hydrolase 1 inhibitor 3-[(3R)-1-[4-(1-benzofu... 4 4
Adenosine receptor A2a ligand 7-(3,4-dimethoxyphenyl)-2-(furan... 6 1
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 9 5
Adenosine receptor A3 ligand CHEMBL1834703 family 2 1
Vascular endothelial growth factor receptor 1 and Vascular end... 11 38
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
Aurora kinase A and Aurora kinase B inhibitor [4-[[7-cyclopent... 1 0
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 3 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 6
Vascular endothelial growth factor receptor 2 and Platelet-der... 16 11
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 3 0
Adenosine receptor A2a and Adenosine receptor A1 ligand 5-[(7S... 6 1
Adenosine receptor A2a ligand 5-[(7S,9aS)-7-[(2-fluorophenoxy)... 5 4
P2X purinoceptor 7 inhibitor SureCN110566 family 1 0
Vascular endothelial growth factor receptor 2 ligand AGN-PC-04... 8 1
Adenosine receptor A2a ligand 3-[(2-bromophenyl)methyl]-8-(fur... 2 0
Adenosine receptor A2a ligand 8-(furan-2-yl)-3-[2-[4-(1,3-thia... 2 2
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 25 5
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 29 1
Adenosine receptor A2a and Adenosine receptor A1 ligand 1-[(2-... 2 0
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 2 1
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 6
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 0
Adenosine receptor A2a ligand SureCN8368237 family 1 0
Adenosine receptor A2a ligand AGN-PC-02Z2S3 family 3 0
Cyclin-dependent kinase 2 and Glycogen synthase kinase-3 beta ... 1 0
Adenosine receptor A3 and Adenosine receptor A1 ligand AGN-PC-... 2 2
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 15 1
Adenosine receptor A2a and Adenosine receptor A1 ligand triazi... 3 0
Serine/threonine-protein kinase Chk1 and Cyclin-A2 inhibitor S... 1 0
Aurora kinase B and Aurora kinase A inhibitor N-(furan-2-ylmet... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00319079 CHEMBL112773 Bioactive SureCN6868032
CFAMM00319092 CHEMBL323945 Bioactive SureCN6874062
CFAMM00319103 CHEMBL110074 Bioactive SureCN6863649
CFAMM00319078 CHEMBL323621 Bioactive SureCN6863149
CFAMM00319091 CHEMBL332718 Bioactive SureCN6870500
CFAMM00319101 CHEMBL113967 Bioactive SureCN6868218
CFAMM00319089 CHEMBL112631 Bioactive SureCN6870198
CFAMM00319088 CHEMBL324077 Bioactive SureCN6867660
CFAMM00319098 CHEMBL110698 Bioactive SureCN6870094
CFAMM00319087 CHEMBL325350 Bioactive SureCN6867961
CFAMM00319080 CHEMBL110069 Bioactive SureCN6867940
CFAMM00319093 CHEMBL325237 Bioactive AGN-PC-01ZMW9
CFAMM00319104 CHEMBL420307 Bioactive SureCN6870197

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26814 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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