CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10753
Family Name Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform inhibitor 1-[6-[5-(tert-butylsulfamoyl)pyridin-3-yl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-3-[2-(2-methyl-1,3-thiazol-4-yl)ethyl]urea family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00404198 Functional Category Bioactive
Superfamily Huntingtin and Prothrombin Binder Superfamily
Class Class 1378

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 13 100
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-07CBUP family 2 3
Cyclin-dependent kinase 2 and Glycogen synthase kinase-3 beta ... 2 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 11
Tyrosine-protein kinase JAK2 and Focal adhesion kinase 1 inhib... 11 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 7 15
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 14 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 2
Fatty-acid amide hydrolase 1 inhibitor 4-(3-phenyl-1,2,4-thiad... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26195 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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