CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10779
Family Name Endothelin-1 receptor and Type-1 angiotensin II receptor ligand 2-[4-[(2-butylbenzimidazol-1-yl)methyl]phenyl]-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzenesulfonamide family
No. of Seeds 6 No. of Other Members 1
Family Centroid CFAMM00404353 Functional Category Bioactive with Natural Product
Superfamily Endothelin-1 receptor and Nuclear receptor ROR-gamma Binder Superfamily
Class Class 3395

Cousin Family NamesSeedsMembers
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 13 23
Endothelin-1 receptor and Endothelin B receptor ligand AGN-PC-... 4 3
Type-1 angiotensin II receptor and Endothelin-1 receptor ligan... 1 1
Endothelin-1 receptor and Endothelin B receptor ligand SureCN7... 1 1


External ID

Functional Category

Molecule Name

CFAMM00404351 CHEMBL2058373 Bioactive 2-[4-[(2-butyl-6-chlorobenzimidazol-1-yl)methyl]phenyl]-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzenesulfonamide
CFAMM00404354 CHEMBL2058374 Bioactive 2-[4-[(6-bromo-2-butylbenzimidazol-1-yl)methyl]phenyl]-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzenesulfonamide
CFAMM00404353 CHEMBL2058370 Bioactive 2-[4-[(2-butylbenzimidazol-1-yl)methyl]phenyl]-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzenesulfonamide
CFAMM00404352 CHEMBL2058371 Bioactive 2-[4-[(2-butyl-6-methylbenzimidazol-1-yl)methyl]phenyl]-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzenesulfonamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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