CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10787
Family Name Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(1,3-benzoxazol-2-yl)piperazin-1-yl]pyrrolidin-2-yl]-(1,3-thiazolidin-3-yl)methanone family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00404390 Functional Category Bioactive
Superfamily Neuropeptide Y receptor type 5 and 5-hydroxytryptamine receptor 6 Binder Superfamily
Class Class 1670

Cousin Family NamesSeedsMembers
Peroxisome proliferator-activated receptor gamma Ligand SB-213... 2 54
Vascular endothelial growth factor receptor 1 and Vascular end... 4 44
Arachidonate 5-lipoxygenase Inhibitor 5-chloro-n-phenylbenzo[d... 3 15
Neutrophil elastase Inhibitor Cbz-val-pro-val-(2-benzoxazole) ... 32 64
5-hydroxytryptamine receptor 3A and Neuronal acetylcholine rec... 2 26
Arachidonate 5-lipoxygenase Inhibitor 5-methyl-n-phenylbenzo[d... 5 13
Arachidonate 5-lipoxygenase Inhibitor 5-methoxy-n-phenylbenzo[... 2 4
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 5 25
Somatostatin receptor type 5 and Potassium voltage-gated chann... 2 21
5-hydroxytryptamine receptor 3A ligand 2-[(3S)-3-ethylmorpholi... 10 18
Prelamin-A/C inhibitor CHEMBL1374443 family 1 6
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 2
Cannabinoid receptor 2 ligand [4-(5-tert-butyl-1,3-benzoxazol-... 4 1
Fatty-acid amide hydrolase 1 inhibitor 2-(1,3-dihydroisoindol-... 2 3
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 7
Orexin receptor type 1 and Orexin receptor type 2 ligand [(2S,... 2 3
Prostaglandin E synthase inhibitor 1-[5-chloro-6-(4-fluorophen... 8 27
Integrin beta-1 and Integrin alpha-4 inhibitor 4-[[(2S,5S)-5-(... 20 10
Gamma-aminobutyric acid receptor subunit pi and Gamma-aminobut... 5 2
Neuropeptide Y receptor type 5 ligand N-(5-chloro-1,3-benzoxaz... 1 1
Cathepsin S and Cathepsin L1 inhibitor (2S)-2-(1,3-benzoxazol-... 1 9
Cathepsin S and Cathepsin L1 inhibitor SureCN5361439 family 2 4
5-hydroxytryptamine receptor 6 ligand SureCN3910449 family 3 15
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor Su... 3 3
Somatostatin receptor type 5 ligand SureCN3572493 family 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00404388 CHEMBL515597 Bioactive SureCN3845455
CFAMM00404386 CHEMBL2058756 Bioactive 2-[4-[(3S,5S)-5-(1,3-thiazolidine-3-carbonyl)pyrrolidin-3-yl]piperazin-1-yl]-1,3-benzoxazole-5-carbonitrile
CFAMM00404390 CHEMBL2058967 Bioactive [(2S,4S)-4-[4-(1,3-benzoxazol-2-yl)piperazin-1-yl]pyrrolidin-2-yl]-(1,3-thiazolidin-3-yl)methanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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