CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10788
Family Name Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(4-phenyl-1,3-thiazol-2-yl)piperazin-1-yl]pyrrolidin-2-yl]-(1,3-thiazolidin-3-yl)methanone family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00404395 Functional Category Bioactive
Superfamily DNA-(apurinic or apyrimidinic site) lyase and Cathepsin K Binder Superfamily
Class Class 1446

Cousin Family NamesSeedsMembers
Prothrombin Inhibitor RWJ-50353 Family 11 95
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-me... 2 45
Cathepsin B and Cathepsin K Inhibitor L-006235-1 Family 19 75
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 4 3
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-264... 6 32
Dipeptidyl peptidase 1 inhibitor (2S)-2-amino-N-[(1S)-2-(1,3-b... 1 1
Histone deacetylase 1 and Histone deacetylase 2 inhibitor AGN-... 2 5
Neuropeptide Y receptor type 5 ligand 2-phenyl-1-[(1R,5S)-6-[[... 9 11
Neuropeptide S receptor and Niemann-Pick C1 protein ligand CHE... 1 1
Protease and Capsid scaffolding protein inhibitor AC1LAC7K family 2 5
Cellular tumor antigen p53 and Protein-cysteine N-palmitoyltra... 1 7
Cathepsin K and Cathepsin S inhibitor (1R,2R)-2-[4-(1,3-benzot... 1 4
Suppressor of tumorigenicity 14 protein and Serine protease he... 6 0
Cathepsin K and Cathepsin L1 inhibitor (2R)-N-(cyanomethyl)-4-... 2 1
Cholinesterase and Acetylcholinesterase inhibitor 3-[ethyl-[3-... 6 9
Serine/threonine-protein kinase Chk1 inhibitor 2-(1,3-dihydroi... 2 5
Histone deacetylase 1 inhibitor N',N'-bis[2-(1,3-benzothiazol-... 2 0
Neuropeptide Y receptor type 5 ligand 2-(dimethylamino)-1-[4-[... 10 5
Neuropeptide Y receptor type 5 ligand 1-[4-[[(9-fluoro-5,6-dih... 11 0
Capsid scaffolding protein inhibitor AC1LAC7W family 2 2
Integrin beta-3 and Integrin alpha-IIb inhibitor 4-[[4-(4-carb... 4 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00404396 CHEMBL2058757 Bioactive [(2S,4S)-4-[4-(1,3-benzothiazol-2-yl)piperazin-1-yl]pyrrolidin-2-yl]-(1,3-thiazolidin-3-yl)methanone
CFAMM00404395 CHEMBL2147702 Bioactive [(2S,4S)-4-[4-(4-phenyl-1,3-thiazol-2-yl)piperazin-1-yl]pyrrolidin-2-yl]-(1,3-thiazolidin-3-yl)methanone
CFAMM00404393 CHEMBL2058758 Bioactive 2-[4-[(3S,5S)-5-(1,3-thiazolidine-3-carbonyl)pyrrolidin-3-yl]piperazin-1-yl]-1,3-benzothiazole-5-carbonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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