CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1079
Family Name Sigma non-opioid intracellular receptor 1 and Mu-type opioid receptor ligand AC1NUHCY family
No. of Seeds 7 No. of Other Members 5
Family Centroid CFAMM00101518 Functional Category Bioactive
Superfamily Mu-type opioid receptor and Delta-type opioid receptor Binder Superfamily 7
Class Class 2771

Cousin Family NamesSeedsMembers
Opioid receptor ligand opiate Levorphanol Family 18 537
Muscarinic acetylcholine receptor M3 Ligand Tolterodine Family 8 171
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Kappa-type opioid receptor Ligand Dezocine Family 36 46
Mu-type opioid receptor Ligand Alvimopan Family 32 325
Eptazocine Hbr family 6 8
Noradrenergic re-uptake and Opioid receptor Ligand Tapentadol ... 21 79
5-hydroxytryptamine receptor 1A Ligand (s)-uh-301 Family 35 20
Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
Estradiol 17-beta-dehydrogenase 1 Inhibitor N-n-diethyl Estrad... 6 16
Estradiol 17-beta-dehydrogenase 1 Inhibitor N-ethyl Estrone-16... 3 5
Sodium-dependent dopamine transporter and Sodium-dependent nor... 9 16
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 18 13
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 44 3
Mu-type opioid receptor Ligand Cyprodime Family 12 8
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 4 0
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 6 2
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 0


External ID

Functional Category

Molecule Name

CFAMM00319140 CHEMBL145296 Bioactive (8E)-5-(3-hydroxyphenyl)-8-[(3-methoxyphenyl)methylidene]-2-methyl-2-azabicyclo[3.3.1]nonan-7-one
CFAMM00319144 CHEMBL143800 Bioactive (8E)-5-(3-hydroxyphenyl)-8-[(4-methoxyphenyl)methylidene]-2-methyl-2-azabicyclo[3.3.1]nonan-7-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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