CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10790
Family Name Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(1H-benzimidazol-2-yl)piperazin-1-yl]pyrrolidin-2-yl]-(1,3-thiazolidin-3-yl)methanone family
No. of Seeds 3 No. of Other Members 5
Family Centroid CFAMM00404418 Functional Category Bioactive
Superfamily Dipeptidyl peptidase 4 and Alpha-1B adrenergic receptor Binder Superfamily
Class Class 3587

Cousin Family NamesSeedsMembers
BIBT986 family 7 96
Dipeptidyl peptidase 4 Inhibitor Teneligliptin Family 13 3
Prothrombin and Cationic trypsin inhibitor (2S)-N-[(2S)-1-(1H-... 4 15
Sterol O-acyltransferase 1 inhibitor 1-(2,4-difluorophenyl)-3-... 8 90
Histamine H4 receptor ligand (2Z)-5-chloro-2-[(1-methylpiperid... 2 8
Histamine H4 receptor and Histamine H3 receptor ligand (E)-[(3... 4 3
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(1-phenylimidaz... 2 1
Orexin receptor type 2 and Orexin receptor type 1 ligand (2S)-... 5 0
Orexin receptor type 2 and Orexin receptor type 1 ligand (2S)-... 2 2
Matrilysin and Stromelysin-1 inhibitor (2R)-N-[(1S)-1-(1H-benz... 3 0
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 2 0
Putative Bioactive N-[(2R)-2-[(2S)-2-(1H-benzimidazol-2-yl)pyr... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00404419 CHEMBL2058761 Bioactive [(2S,4S)-4-[4-(6-chloro-1H-benzimidazol-2-yl)piperazin-1-yl]pyrrolidin-2-yl]-(1,3-thiazolidin-3-yl)methanone
CFAMM00404418 CHEMBL2058760 Bioactive [(2S,4S)-4-[4-(1H-benzimidazol-2-yl)piperazin-1-yl]pyrrolidin-2-yl]-(1,3-thiazolidin-3-yl)methanone
CFAMM00404420 CHEMBL2058762 Bioactive 2-[4-[(3S,5S)-5-(1,3-thiazolidine-3-carbonyl)pyrrolidin-3-yl]piperazin-1-yl]-3H-benzimidazole-5-carbonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27272 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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