CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10794
Family Name Type-1 angiotensin II receptor ligand 7-methyl-N-(2-phenylethyl)-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-5-carboxamide family
No. of Seeds 2 No. of Other Members 10
Family Centroid CFAMM00404492 Functional Category Bioactive
Superfamily Cholecystokinin receptor type A and Platelet-activating factor receptor Binder Superfamily
Class Class 3805

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand be... 4 301
5-hydroxytryptamine receptor Ligand Ramosetron Family 10 219
Tubulin beta chain Inhibitor Mebendazole Family 12 84
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 5 129
NS5A protein Inhibitor Bms 790052 Family 5 9
BIBT986 family 7 96
Vascular endothelial growth factor receptor 1 and Angiopoietin... 29 127
CC-486 family 7 103
Integrin alpha-V and Integrin beta-3 Inhibitor SB-223245 Family 27 36
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[c... 20 18
Adenosine receptor A1 and Adenosine receptor A2a Ligand OSIP-3... 4 31
Telomerase reverse transcriptase Inhibitor NSC-745794 Family 3 1
DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-57893 Family 3 8
Type-2 angiotensin II receptor Ligand L-158809 Family 22 136
RAC-gamma serine/threonine-protein kinase Inhibitor BMS-754807... 20 90
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
Prothrombin and Cationic trypsin inhibitor (2S)-N-[(2S)-1-(1H-... 4 15
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-4-... 4 10
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 27
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 6
Peroxisome proliferator-activated receptor gamma ligand 1-[(4-... 7 29
Gonadotropin-releasing hormone receptor ligand 1-(7-azabicyclo... 4 4
Gonadotropin-releasing hormone receptor ligand 1-(3-azabicyclo... 9 10
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QM1E family 8 15
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-0A9QGC ... 14 0
C-C chemokine receptor type 5 ligand [4-[2-[3-(2-ethylbenzimid... 5 12
Coagulation factor X inhibitor AGN-PC-0749BY family 5 9
Histamine H3 receptor and Potassium voltage-gated channel subf... 7 1
Protein-tyrosine kinase 6 and KH domain-containing, RNA-bindin... 21 6
Coagulation factor X and Coagulation factor IX inhibitor 5-ami... 9 4
Histamine H1 receptor and Histamine H4 receptor ligand [4-[2-[... 1 1
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 10
Coagulation factor X inhibitor SureCN8289965 family 4 5
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 4 29
Casein kinase II subunit alpha and Serine/threonine-protein ki... 1 5
Vascular endothelial growth factor receptor 2 ligand (3Z)-6-fl... 4 3
Type-1 angiotensin II receptor ligand N-[2-(3-methoxyphenyl)et... 2 0
Cyclin-dependent kinase 2 and Serine/threonine-protein kinase ... 2 2
Type-1 angiotensin II receptor and Type-1A angiotensin II rece... 8 0
Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2 ... 3 2
Tyrosine-protein kinase ABL1 and Breakpoint cluster region pro... 12 0
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 0
Melanocortin receptor 4 ligand AGN-PC-076AMO family 17 8
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 4 3
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... 9 2
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 35 14
Type-1 angiotensin II receptor ligand 2-[(2-ethyl-5,7-dimethyl... 5 3
Coagulation factor X and Coagulation factor IX inhibitor 5-ami... 1 1
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 5 1
Glucagon receptor and Gastric inhibitory polypeptide ligand Su... 9 1
Glucagon receptor ligand SureCN2666184 family 7 2
Aurora kinase A and Aurora kinase B inhibitor N-[(3E)-3-[5-(mo... 3 2
Platelet-derived growth factor receptor beta and Fibroblast gr... 2 1
Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymeras... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00404492 CHEMBL2058859 Bioactive 7-methyl-N-(2-phenylethyl)-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-5-carboxamide
CFAMM00404498 CHEMBL2058860 Bioactive 7-methyl-N-(2-phenylpropyl)-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-5-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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