CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM10796
Family Name Poly [ADP-ribose] polymerase 1 inhibitor 8-[[4-fluoro-3-(4-phenylpiperazine-1-carbonyl)phenyl]methyl]-2,3,4,6-tetrahydro-1H-pyrido[2,3-d]pyridazin-5-one family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00404506 Functional Category Bioactive
Superfamily Poly [ADP-ribose] polymerase 1 and Gonadotropin-releasing hormone receptor Binder Superfamily
Class Class 2794

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Palonosetron Family 12 403
Poly [ADP-ribose] polymerase 1 Inhibitor KU-0059436 Family 21 45
Poly [ADP-ribose] polymerase 1 Inhibitor KU-58684 Family 6 40
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 9 8
B1 bradykinin receptor ligand 4-(4-methyl-1-oxophthalazin-2-yl... 5 27
Melanin-concentrating hormone receptor 1 ligand N-[3-[1-[3-[4-... 4 13
Poly [ADP-ribose] polymerase 1 inhibitor 2-fluoro-N-[2-(4-meth... 11 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 2 0
Poly [ADP-ribose] polymerase 1 inhibitor Piperazine analogue, ... 1 0
Poly [ADP-ribose] polymerase 1 inhibitor 3-[[4-fluoro-3-[4-(2-... 15 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00404507 CHEMBL598752 Bioactive 3-[[3-[4-(1-anilinocyclopentanecarbonyl)piperazine-1-carbonyl]-4-fluorophenyl]methyl]-4,5-dimethyl-1H-pyridazin-6-one
CFAMM00404506 CHEMBL2058923 Bioactive 8-[[4-fluoro-3-(4-phenylpiperazine-1-carbonyl)phenyl]methyl]-2,3,4,6-tetrahydro-1H-pyrido[2,3-d]pyridazin-5-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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